Guesthouse vacation rentals in Anderson County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Anderson County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Anderson County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Pendleton
4.89 out of 5 average rating, 251 reviewsLa Bella Farm
Guesthouse in Anderson
4.93 out of 5 average rating, 247 reviewsBe Our Guest
Guesthouse in Liberty
4.93 out of 5 average rating, 189 reviewsHolly Hideaway! 10 Highway miles to Clemson U!
Private room in Pelzer
4.98 out of 5 average rating, 123 reviewsSouth Oaks Guesthouse
Guesthouse in Donalds
4.99 out of 5 average rating, 359 reviewsHome on the farm
Guesthouse in Townville
4.86 out of 5 average rating, 247 reviewsLisa’s Lodge
Guest house rentals with a patio
Guesthouse in Seneca
5 out of 5 average rating, 31 reviewsOne Particular Cove ... on Lake Hartwell
Guesthouse in Townville
5 out of 5 average rating, 18 reviewsCharming Waterfront Guest House
Guesthouse in Hartwell
4.97 out of 5 average rating, 76 reviewsOne bedroom lake front apartment with free parking
Guesthouse in Clemson
5 out of 5 average rating, 37 reviewsDowntown Clemson Guest Suite!
Guesthouse in Clemson
5 out of 5 average rating, 20 reviewsAdorable Cottage 2 mi. from Death Valley
Guesthouse in Honea Path
4.89 out of 5 average rating, 35 reviewsThe Honey Flat
Guesthouse in Central
5 out of 5 average rating, 13 reviewsVacation Home Clemson and Lakes
Guesthouse in Piedmont
4.99 out of 5 average rating, 69 reviewsShou-Sugi-Ban Retreat on the Saluda River
Guest house rentals with a washer and dryer
Guesthouse in Townville
5 out of 5 average rating, 9 reviewsParadise Point on Lake Hartwell
Guesthouse in Clemson
4.93 out of 5 average rating, 14 reviewsClemson Carriage House - NEW!
Guesthouse in Townville
4.8 out of 5 average rating, 5 reviewsBeautiful Luxury home on Lake Hartwell by Clemson
Guesthouse in Anderson
4.94 out of 5 average rating, 182 reviewsPrivate - No storm damage! - Lake getaway
Guesthouse in Anderson
4.86 out of 5 average rating, 7 reviewsCozy 2BR lakeside apt w dock near marina & Clemson
Guesthouse in Clemson
5 out of 5 average rating, 12 reviewsRiggs Drive Gameday Getaway
Destinations to explore
- Guesthouse rentals United States
- House rentals United States
- House rentals Great Smoky Mountains
- Guesthouse rentals Great Smoky Mountains
- House rentals Gatlinburg
- House rentals Asheville
- Guesthouse rentals Asheville
- Guesthouse rentals South Carolina
- House rentals South Carolina
- Kid-friendly rentals Anderson County
- Rentals with a washer and dryer Anderson County
- Rentals with lake access Anderson County
- House rentals Anderson County
- Pet-friendly rentals Anderson County
- Apartment rentals Anderson County
- Rentals with a fireplace Anderson County
- Waterfront rentals Anderson County
- Rentals with outdoor seating Anderson County
- Cabin rentals Anderson County
- Rentals with breakfast Anderson County
- Rentals with an EV charger Anderson County
- Monthly Rentals Anderson County
- Fitness-friendly rentals Anderson County
- Rentals with a hot tub Anderson County
- Rentals with pools Anderson County
- Rentals with a fire pit Anderson County
- Rentals with a patio Anderson County
- Private suite rentals Anderson County
- Rentals with a kayak Anderson County
- Condo rentals Anderson County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom