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Vacation rentals in Mira Mesa, San Diego

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Top-rated vacation rentals in Mira Mesa, San Diego

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guesthouse in Rancho Bernardo

4.92 out of 5 average rating, 702 reviews

Hilltop cabin retreat with lake & mountain views

Rustic hilltop cabin overlooking Lake Hodges. Surrounded by open canyons & mountains, you will feel like you're a million miles away from everything as you take in the views from the cabin, deck or the outside shower, swim in the saltwater pool, or relax by the fire bowl. A short walk to lake with boating, fishing & miles of hiking/mountain biking trails. Property offers swimming pool, fire bowl, and shaded arbor. SD Zoo Safari Park, wineries, breweries, & ocean beaches all within easy reach.

Guest suite in San Diego

4.96 out of 5 average rating, 357 reviews

The 5 C's Studio: 15 min to the Beach w/ Backyard

*If interested in booking for longer than 28 nights pls send us a request and don’t instant book.* 15min to the beach, this inviting studio is filled w/ amenities & hosted with a 5 star experience. Perfect for couples, families and business travelers. The vibe is a mashup of European sophistication, West African artifacts & Brazilian charisma. The 5 C’s Studio, hits all your senses - sparkling CLEAN. CENTRAL to all attractions. CLASSY, and CALMING for all. In the heart of CA’s finest city!

Guesthouse in Solana Beach

4.98 out of 5 average rating, 457 reviews

Quiet cottage AC near beach in nice private yard.

Private cottage in a great neighborhood close to the beach. Cottage has an air conditioner/heater, queen bed, kitchen, bathroom, & TV & desk. Washer & dryer available. Fletcher cove is 1/2 mile by car or walk. Walking distance to Cedros Shopping district that has boutiques, restaurants & coffee houses. The Belly Up Tavern, Del Mar Race Track & Fairgrounds and fine restaurants are nearby. It is a short walk to the trailhead to San Elijo Lagoon Preserve hike and Annie's canyon.

Rental unit in Serra Mesa

4.98 out of 5 average rating, 428 reviews

Lovely spacious upstairs studio with private entry

You’ll love our place as its spacious, quiet, private, comfortable in a residential neighborhood. The king-size bed is extremely comfortable and we have big relaxing patio chairs on our large balcony overlooking a beautiful landscaped garden. We are centrally located to most all of San Diego's attractions and close to freeways. The famous Gaslamp, Zoo, downtown and beaches are all within 13 to 20 minute drive. The kitchen is stocked with goodies, coffee and an assortment of teas.

Guesthouse in Mira Mesa

4.96 out of 5 average rating, 160 reviews

super clean studio/private entrance&parking

Newly remodelled studio with private entrance and 1 reserved drive way parking spot in an upscale neighborhood. Bright color designs will bring you good mood and energy. Neighborhood is quiet and safe, near Sorrento valley, La Jolla and Del Mar beach. So many good restaurants and markets around. I'm an interior designer and really care about how my guests feel during their stays. When I designed and built this unit, I choose all unique materials that bring you the best experience.

Guest suite in Mira Mesa

4.89 out of 5 average rating, 114 reviews

Stunning Private Entrance 2bd/1ba Suite

Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Home in Mira Mesa

4.94 out of 5 average rating, 282 reviews

Contemporary Family-Friendly Home in SD with EV&AC

Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Guest suite in Mira Mesa

4.94 out of 5 average rating, 100 reviews

*Super cute* modern studio with private entrance!

☀️ Newly renovated, private guest suite with its own separate entrance; close to all the best parts of San Diego! 🖥️ It comes with AC/heat, a 55-inch TV with 85+ channels, high-speed internet, mini-fridge and freezer, kitchenette with induction cooktop and microwave. 💦 Guests LOVE the modern bathroom with a rainfall shower head. ✅ EASY, 24/7 self check-in with smart lock! 🏝️ Super close to freeways and just 20 minutes from downtown, the airport, beaches and UCSD!

Guest suite in Escondido

4.94 out of 5 average rating, 315 reviews

Cozy Hilltop Garden Studio w/ City Views & Jacuzzi

Beautiful garden level basement studio on top of a hill overlooking the city (guest suite underneath main home). The studio features a separate, private entrance with captivating views of both the backyard garden and city skyline. Enjoy access to the backyard which includes a large deck and entertaining space as well as an outdoor fireplace & jacuzzi. Inside the studio is a large tv center with netflix, amazon, hulu and starz included in addition to high speed wifi.

Tiny home in Rancho Penasquitos

4.9 out of 5 average rating, 177 reviews

WOW! Private Studio Minutes To Shopping& Freeways.

Entire Private Studio Suite. Brand new up dated entire suite with 1 Queen Bed & 1 bath. Ideal for couples, solo adventurers, and business travelers. Studio is fully equipped with 1 queen bed, 1 working desk, kitchenette meant for light food warm, mini size refrigerator, single sink meant for light cup and dish wash. All new furniture, mattress, beddings. All shops, restaurants, cinema, hiking trails within minus drive about 1-5 miles away!

Guesthouse in San Diego

4.91 out of 5 average rating, 190 reviews

Central studio w/ private outdoor space & parking

Studio unit with ample free street parking in safe quiet SD suburb. Private entrance with outdoor patio, fully fenced in and safe for pets. Full kitchen and cozy studio w/ a comfy queen bed. Close to the freeway, very easy access to all major SD attractions without the hassle of traffic! Pacific Beach: 3.6 miles La Jolla Shores: 3.7 miles Airport: 7.3 miles Little Italy: 7.4 miles Balboa Park: 7.8 miles SD Zoo: 7.4 miles

Guest suite in San Diego

4.87 out of 5 average rating, 101 reviews

Modern Guest Suite in North San Diego

Enjoy this stylish and spacious guest suite with kitchen, living room, laundry room, one bedroom and walk-in closet in a newly built community with access to the club house (fitness room, swimming pool, hot spa and BBQ grills). Convenience location - within 30 min drive to Legoland, SeaWorld, SD Zoo, SD Safari Park, Balboa Park, Qualcomm and UCSD. Best school district in SD. Extra Discount to weekly and monthly stay!

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Popular amenities for Mira Mesa, San Diego vacation rentals

Free parking on premises

Air conditioning

Stay near Mira Mesa, San Diego's top sights

Lake Miramar41 locals recommend

Vons51 locals recommend

Ballast Point Brewing Miramar48 locals recommend

Regal Edwards Mira Mesa 4DX, IMAX & RPX38 locals recommend

Green Flash Brewing31 locals recommend

Jack in the Box29 locals recommend

Other great vacation rentals in Mira Mesa, San Diego

Condo in Torrey Hills

5 out of 5 average rating, 17 reviews

Perfectly Furnished and Located 1 Bedroom Condo

Guest suite in Rancho Penasquitos

4.82 out of 5 average rating, 55 reviews

Adorable ADU Studio (attached), w easy street pkng

Guest suite in San Diego

4.85 out of 5 average rating, 87 reviews

The Black and White Suite at Torrey Highlands

Guesthouse in Mira Mesa

5 out of 5 average rating, 61 reviews

Modern and Spacious Guest House

Guesthouse in Rancho Penasquitos

4.94 out of 5 average rating, 99 reviews

❤ Cozy Private Studio w/ WD 2 Minutes from Freeway

Guest suite in San Diego

4.97 out of 5 average rating, 72 reviews

Adorable suite 1-bedroom in San Diego

Guest suite in University City

4.88 out of 5 average rating, 51 reviews

Private Casita - Guest suite with full bath

Home in Scripps Miramar Ranch

4.88 out of 5 average rating, 48 reviews

20% OFF- Newly updated guesthome for families

Quick stats about vacation rentals in Mira Mesa, San Diego

Total rentals
290 properties
Total number of reviews
12K reviews
Family-friendly rentals
100 properties are a good fit for families
Pet-friendly rentals
40 properties allow pets
Rentals with a pool
60 properties have a pool
Rentals with dedicated workspaces
180 properties have a dedicated workspace

Destinations to explore