House vacation rentals in Orangeburg County
Find and book unique houses on Airbnb
Top-rated house rentals in Orangeburg County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Orangeburg County house rentals
House rentals with a pool
Home in Orangeburg
4.96 out of 5 average rating, 67 reviewsColonial Farmhouse - 6 bedroom with a pool
Home in Eutawville
4.92 out of 5 average rating, 13 reviewsLakeview Leisure-Face to the Sun
Home in Williston
4.91 out of 5 average rating, 22 reviewsOut Aways House with a POOL on a POND
Home in Santee
5 out of 5 average rating, 7 reviewsThe Merry Inn @ Lake Marion
Home in Eutawville
4.94 out of 5 average rating, 52 reviewsHeated Indoor Pool/Lake Front and Dock
Home in Santee
4.95 out of 5 average rating, 38 reviewsLakefront Lookout
Weekly house rentals
Home in Summerton
4.72 out of 5 average rating, 18 reviewsSpacious fishing house in the heart of goat island
Home in Santee
4.97 out of 5 average rating, 153 reviewsSantee lakefront home, big water right off I-95
Home in Orangeburg
4.83 out of 5 average rating, 18 reviewsRayneBow Royalty
Home in Orangeburg
New place to stayRussell House
Home in Summerton
4.94 out of 5 average rating, 36 reviewsCozy 3 bed 2 bath on the waterfront
Home in Olar
4.91 out of 5 average rating, 23 reviewsStrawberry Farm House
Home in Denmark
4.84 out of 5 average rating, 77 reviewsCome home and relax at The Denmark Retreat!!
Private house rentals
Home in Eutawville
5 out of 5 average rating, 8 reviewsLake House at Lake Marion
Home in Bamberg
5 out of 5 average rating, 6 reviewsCharming Bamberg Home Near Medical Centers!
Home in Summerton
4.85 out of 5 average rating, 46 reviewsFamily friendly lakefront home with boat ramp
Home in Summerton
4.74 out of 5 average rating, 54 reviewsFlip Flop Inn - Short Walk to Boat Ramp!
Home in Orangeburg
4.67 out of 5 average rating, 12 reviewsCozy, Quiet, 2 Bedroom House
Home in Santee
4.87 out of 5 average rating, 23 reviewsCarolina Bea Hive: Lakeside Modern Home+Games+Doc
Home in Elloree
4.75 out of 5 average rating, 8 reviewsCountry Resting Spot
Home in North
5 out of 5 average rating, 3 reviewsFarmhouse Chic StayCation Retreat
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