Hotel vacation rentals in Santa Fe de Antioquia

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Santa Fe de Antioquia

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Casa particular in Laureles-Estadio

4.97 out of 5 average rating, 92 reviews

Enjoy the best location

Quiet spot. In one of the “more coolest” neighborhoods in the world; according to Time Out magazine (2023). With all the transportation offer minutes from your location. Walking distance to the best in gastronomy, spirits, rumba, sports, universities and health, such as: Atanasio Girardot Stadium Stadium, Floresta Metro Station, Boulevard de la 70, Parks de Laureles, Pueblito Paisa, Plaza de Convenciones, Plaza de Toros, Parks del rio, Comuna Trece, Plaza retailer for vegetables and fruits.

Guest favorite

Hotel room in El Poblado

4.9 out of 5 average rating, 68 reviews

9 bedrooms-Private pool-Jacuzzis-Free Breakfast

This unique boutique house with a private pool and multiple Jacuzzis with breakfast and daily cleaning included. The house is equipped with multiple living rooms, nine bedrooms with attached bathrooms and large screen HD TVs in each bedroom, two kitchenettes, a full kitchen, modern furniture and decor. In addition to this, guests have free access to one of the best rooftops in Medellin, located a few blocks away, where they can enjoy the heated pool, the bar and a beautiful 360° view of the city

Superhost

Hotel room in San Diego

4.83 out of 5 average rating, 18 reviews

Beautiful and peaceful farmhouse with great views

Lleva a toda la familia o a tus mejores amigos a este fantástico lugar con muchas zonas para divertirse. contamos con 1200metros de terreno solo para ti, hermosa casa de campo en las únicas colinas de Girardota, disfrutaras de la tranquilidad, privacidad, conexión con la naturaleza y presenciaras un bello atardecer sin igual, quédate y observa las estrellas, podrás entrar en contacto con nuestros animales, espacios aptos para unas fotos únicas de recuerdo. Area ideal para ciclismo y senderismo.

Guest favorite

Casa particular in Laureles-Estadio

4.85 out of 5 average rating, 34 reviews

Beautiful Colonial Apartment in Laureles - MDE

Welcome to your home away from home in Medellín! Nestled in the heart of Laureles, one of Medellín’s most vibrant neighborhoods, this spacious 4-bedroom house offers the perfect blend of comfort, convenience. Step outside and you’ll find yourself in the heart of Medellín’s bustling city life. From convenience stores and supermarkets to pharmacies and restaurants, everything you need is just a stone’s throw away. Book with us today and make this your home during your unforgettable adventure.

Guest favorite

Hotel room in El Poblado

4.93 out of 5 average rating, 101 reviews

Standard Room A/C WiFi and Free coworking-Provenza

Te invitamos a descubrir la zona más cool de Medellín! Si bien las habitaciones son iguales en su tamaño y dotación, hemos añadido un toque especial a cada una de ellas con sutiles diferencias en la distribución de su mobiliario. Esto significa que cada visita puede ser una experiencia única, pero siempre con la misma base de comodidad, funcionalidad y exclusividad que te ofrecemos. La esencia de cada habitación es la misma, brindándote una experiencia consistente y confortable.

Guest favorite

Hotel room in El Poblado

4.97 out of 5 average rating, 103 reviews

Luxurious 2 Bedroom Poblado Near Provenza Energy

Excited to come visit Medellin? Not sure where to stay? This is by far one of the best places you can book here in Medellin (and believe me, I've stayed in many). Located in El Poblado, close to Provenza, this luxurious 2-bedroom apartment is located in the Energy Living building, one of Medellin's most well-known and desired AirBnB hotels. Incredible amenities, excellent value, comfortable, and secure. One of the best bang-for-buck options you will find!

Superhost

Hotel room in El Poblado

4.8 out of 5 average rating, 104 reviews

MARRIE´S ROOM POBLADO MANILA MEDELLIN Nº 2

Welcome to Algo De Nosotros - ADN, a cozy hostel with a decoration inspired by elements of nature such as wood, plants and natural light. The town is located in the sector, inside a safe neighborhood called Manila. _Entorno: Metro and a large supermarket (5 minutes on foot), restaurants, shops, private parking next door (with discount for ADN hostel guests), 10 minutes parque lleras (nightlife area). _5 private rooms w / own bathroom. _WIFI free

Guest favorite

Casa particular in Envigado

4.86 out of 5 average rating, 14 reviews

House among nature for families and groups.

Quiet and safe environment, indoor and outdoor, suitable for sharing with family, relaxing or working; close to shopping centers, supermarkets, cinemas and fun, street of the good table, easy to get to the center of envigado on foot or public transport, parking included. The 4 bedrooms with double beds, 3.5 bathrooms, outdoor deck, TV area, high speed wifi. Sex tourism is not allowed, no parties or the use of vice or hallucinrogens.

Guest favorite

Hotel room in El Poblado

4.96 out of 5 average rating, 233 reviews

Room for 2 people with breakfast included

The Lettera Hotel is located in the exclusive sector of El Poblado in Medellin. In the residential sector and a few minutes' walk from Provence, one of the fastest growing gastronomic and fun areas in the city, near Parque Lleras. We have comfortable rooms equipped with Smart TV, Security Cajila, minibar, desk, amenities and more that will make you feel at home. At Lettera Hotel we write stories, come live your own!

Guest favorite

Hotel room in Santa Fe de Antioquia

5 out of 5 average rating, 7 reviews

Fabulous private bedroom

Charming room with air conditioning and double bed surrounded by a warm and quiet atmosphere where colors and alternative design make the space an experience that balances privacy and comfort with the ability to connect and share with other guests. Common spaces include a refreshing pool, bar, open kitchen, fans, and living areas to work or comfortably clear.

Superhost

Hotel room in El Poblado

4.82 out of 5 average rating, 1,085 reviews

Small Superior in El Poblado - Hashtag 98 Hotel

You will enjoy this room of 20 m² (215 ft²) and this modern accommodation that is located in the most exclusive sector of Medellín, 3 minutes walk from Parque Lleras and 7 minutes from Provence, where you will find the most recognized restaurants and the best rumba sites. On the top floor you will find our wonderful Rooftop

Guest favorite

Hotel room in El Poblado

4.87 out of 5 average rating, 325 reviews

574 Hotel - Double Bedroom + Breakfast Included + Netflix

Our room comes with a Double Bed, Air Conditioning, HIgh-speed Internet, TV with Netflix, Toiletries, Open Closet. and a Comfortable Desk. We offer our FREE breakfast in Caimán - our outdoors cafe - where you will find as well pastries and plates from our tasty and delicious Colombian Cuisine.