We’re sorry, some parts of the Airbnb website don’t work properly without JavaScript enabled.

Airbnb your place

Vacation rentals in Sisquoc

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Sisquoc

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guesthouse in Santa Maria

4.89 out of 5 average rating, 216 reviews

Cottage On The Court: Wineries Beaches Sport Court

Nestled in an upscale private neighborhood you'll find your own personal space on the central coast. Enjoy hikes, dining and wineries in Orcutt or travel the short distances to San Luis Obispo, Pismo/Avila Beaches, Solvang/Santa Ynez, Santa Barbara and Lompoc (VSFB) to enjoy more of our beautiful coastline where the weather is almost always perfect 🏓🏀Our outdoor amenities are what really make this cottage stand out. With a private Tennis/Pickleball/Basketball court right outside your back door

Guest suite in Santa Maria

4.87 out of 5 average rating, 763 reviews

Estate Guest Home—Upstairs, EV Charger on site

Chic exclusive private guest home with Kitchenette & Full bathroom in the heart of wine country.Home is upstairs above a 4 car garage attached to an Estate Home (No Shared walls).The Estate homes kitchen windows are adjacent to the guest home windows.When all the windows are open you may hear me in my kitchen as I am cooking or baking. One mile off the 101. Close to VAFB (20 mins), 1 hr to Santa Barbara.Orcutt is full of wine tasting rooms and restaurants.Orcutt is small & closes about 9 pm.

Home in Los Alamos

4.85 out of 5 average rating, 300 reviews

Bodega House

Welcome to Bodega House! We can't wait to host you at our charming 1920s farmhouse in Los Alamos. Enjoy the chef's kitchen, private patio, and two cozy bedrooms while soaking up Santa Ynez Valley wine country. Our wine and beer garden, Bodega, is also on the property and features a retail shop, bocce ball, and a greenhouse filled with unique plants and pottery. Check it out and relax by the fire pit with a glass of wine during Bodega's business hours. Bodega is open Thursday - Sunday, 12-7 pm.

Guesthouse in Buellton

4.95 out of 5 average rating, 390 reviews

Wine Country Cottage

Experience the tranquil ambiance of the Wine Country Cottage's serene surroundings. Bask in the breathtaking views of rolling hills and grazing cattle while savoring your favorite bottle of wine from the comfort of our deck. You will be charmed by the presence of Jack & Henry, our Mini Donkeys. As the sun sets, indulge in the magical allure of the outdoor fairy lights and cozy up by the inviting fire pit. Come and relish in the alluring tranquility that awaits you at the Wine Country Cottage.

Home in Santa Maria

4.93 out of 5 average rating, 344 reviews

Beautiful Home, Central Coast

Beautiful spacious 4 bedroom, 3 bath home w/garage. Downstairs a newly remodeled kitchen with all new cabinets, stainless appliances, wine fridge, formal living and dining room and 1/2 bath ( no shower). Upstairs all 4 bedrooms w/ ceiling fans, 2 full baths and laundry room. Large lot w/ beautiful landscaped backyard w/ 2 patio tables and gas bbq. Located between San Luis Obispo and Santa Barbara. Close to Pismo Beach, Avila Beach, hiking trails, Chumash Casino, golf courses & many wineries.

Cottage in San Luis Obispo

4.96 out of 5 average rating, 378 reviews

Peaceful Cottage in an Olive Grove

Come relax in this cozy cottage removed from the frantic world but so close you can easily go back at any time. Whether you choose to unwind in the serenity that surrounds our olive farm or venture out to experience all that SLO County has to offer, you'll be in the perfect spot for either or both. We're on a road less traveled with neighbors few and far between but located just 10 minutes from wine tasting, beaches, downtown SLO, the Village of Arroyo Grande, hiking trails and so much more.

Home in Los Alamos

5 out of 5 average rating, 134 reviews

Centennial House - Old West meets Modern Farmhouse

Ideally located in the heart of Los Alamos, Centennial House is perfect for your next getaway. Explore artisanal dining, wine tasting, and antiquing adventures a short walk away, or relax on the expansive, adobe style front porch with a glass of Grenache made by one of our local female winemakers in hand. Enjoy the fine dining, hip happenings of Bell’s across the street and say howdy to the local caballeros riding down the road. Experience Santa Barbara Wine Country like never before!

Guesthouse in Ballard

4.78 out of 5 average rating, 884 reviews

Rustic retreat

This cottage is very comfortable and cute. It is rustic but we have AC and heat for every season. The outside has a lovely courtyard with fire pit and string lights. This cottage is very centrally located with Los Olivos just a mile up the road and Solvang 3 miles down the road. There are many wineries in every direction walking distance and a bike ride away. It sleeps two comfortably in our queen size bed. Please let us know the duration of time in which she would like to stay.

Guesthouse in Arroyo Grande

4.96 out of 5 average rating, 222 reviews

Quiet Country Cottage

Located 15 minutes (10 miles) down a rural country road East of the historic village of Arroyo Grande, offers beautiful views of surrounding hills and wildlife, including grazing cattle and wild turkeys. The cottage studio has a comfy queen size bed, satellite TV, bathroom with shower, unlimited WiFi, and a sunny private patio. Relax in a private patio, feed our chickens & visit our garden. Our 2 friendly, outdoor dogs and cat will happily welcome you upon arrival!

Guesthouse in Santa Maria

4.99 out of 5 average rating, 1,534 reviews

French Country Casita - Breakfast Included

This stand-alone casita sits in the privacy of our rear yard and has a separate entrance. We are three minutes from highway 101 in the newer La Ventana community. Surrounded by beautiful mountain views on the Central Coast and close to many flourishing wineries, this residence is 20 minutes south of Pismo Beach, 30 minutes from San Luis Obispo, one hour north of Santa Barbara, close to the beautiful Danish city of Solvang and Santa Ynez.

Guest suite in Solvang

4.97 out of 5 average rating, 1,153 reviews

Nogmo Farm Studio

Studio with private entrance, bathroom, Queen sized bed, and sleeper sofa. Walking distance to grocery store. 3 min drive to downtown Solvang. 8 min drive to Los Olivos. For couples, adventurers, and business travelers. Kitchenette has a small fridge, sink, coffee maker and hot water kettle. No stove or microwave inside the studio. Apple TV in the studio. Sorry, no pets allowed. We will provide a pack n’ play for babies.

Guest suite in Morro Bay

4.95 out of 5 average rating, 893 reviews

*Seaside-Village Cottage*

Our motto- "Travelers should be spoiled!" Enjoy the treasures of California's Central Coast -beaches, vineyards, and shopping- then return to a comfortable, cozy king size bed in a quiet neighborhood. We are located on the EAST side of Highway One. A five minute walk puts your toes in the sand and renew your spirit! :)) **We do have a cat; Apollo can be curious. Primarily, Apollo lives upstairs with us.

Vacation rentals for every style

Get the amount of space that is right for you

Hotels

Stylish accommodations and amenities

Unique stays

Spaces that are more than just a place to sleep

Homes

Comfortable places with all the essentials

Popular amenities for Sisquoc vacation rentals

Free parking on premises

Air conditioning

Other great vacation rentals in Sisquoc

Loft in Nipomo

4.94 out of 5 average rating, 785 reviews

Upstairs Guest Loft~EV Charge/Non-smoking/Pet-free

Bungalow in Santa Maria

4.88 out of 5 average rating, 250 reviews

Entire Craftsman Home Central Coast Hub

Guesthouse in Santa Maria

4.97 out of 5 average rating, 93 reviews

Private top floor spacious 1 bedroom retreat

Guesthouse in San Luis Obispo

4.98 out of 5 average rating, 528 reviews

SLO Guesthouse - quiet - near downtown - #115545

Cottage in Los Alamos

4.99 out of 5 average rating, 160 reviews

Camp Cottonwood

Guest suite in Santa Maria

4.9 out of 5 average rating, 71 reviews

Country stay nestled in town. Private entrance.

Guest suite in Arroyo Grande

4.99 out of 5 average rating, 392 reviews

Bright Nature Oasis by the Historic Village!

Home in Santa Maria

5 out of 5 average rating, 31 reviews

Central Coast Gem (Orcutt)

Destinations to explore