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Guesthouse vacation rentals in Central Illinois

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Central Illinois

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guesthouse in Eureka

4.75 out of 5 average rating, 101 reviews

Artist Loft

Artist Loft in a small town. Completely detached from the main house, one big room for living and sleeping with a queen sized bed for your comfort, a private bathroom with glass shower, and ceramic tile. Gas fireplace for fall/winter, and air conditioning for spring/summer. Big screens and sliding doors allow fresh air. Singles or couples will love hanging out in this special place. Private deck for day or night. This deck is perfect for your coffee or a glass of wine. Or enjoy a fire outback.

Guesthouse in Jerseyville

4.97 out of 5 average rating, 115 reviews

Cozy cabin on farm near Jerseyville and Grafton IL

No cleaning fees! Relax in this cozy cabin on a 30 acre farm w/beautiful views & peaceful surroundings. Near shopping, wineries, nightlife, hunting & fishing. Abundant wildlife & farm animals-horses, cows, chickens, goats, sheep, geese. Two bedrooms (one in a spacious loft) with a queen sofa sleeper in the living room. Full kitchen w/dish washer. Fireplace & cathedral ceilings in living room. Full bath w/shower. Covered front porch. Screen porch off living area w/outdoor seating. Fire pit.

Guesthouse in Berwick

4.98 out of 5 average rating, 219 reviews

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Guesthouse in Terre Haute

4.96 out of 5 average rating, 184 reviews

College Cottage

Centrally located to 3 colleges and 2 hospitals in a peaceful neighborhood, this cozy, open concept studio guesthouse is perfect for a short- or long-term stay. This newly renovated garage apartment to guesthouse requires no steps and features a spacious fenced in area for your pet. Creativity abounds in this uniquely decorated space. It features a king-sized bed as well as queen sized sofa sleeper. The kitchen is well stocked and has a coffee/tea bar for your enjoyment. Pets are welcome.

Guesthouse in Terre Haute

5 out of 5 average rating, 164 reviews

10th Street Studio

Welcome to 10th Street Studio! This unit is very spacious, clean, quiet and comfortable. It is located on a quiet street in the Collett Park neighborhood, just minutes to Union Hospital, ISU, and downtown. It is a perfect location for traveling nurses and out of town workers as well as overnight guest passing through town, or those visiting family, friends or students. There is no extra cleaning fees and we offer discounts for weekly and monthly stays. I look forward to hosting you!

Guesthouse in Chesterton

4.96 out of 5 average rating, 154 reviews

Bro’s Place

Welcome if you like country life Bro’s place is the place to be...watching the sheep, chickens and wildlife on you back deck making dinner on the grill with a full kitchen. Pick your own veggies outside the back door when in season. You will find a welcome basket with snacks, wine and homemade soap in bathroom fresh eggs from our chickens when available if your planning to visit our Beautiful Indiana Dunes you’ll find everything you need..chairs, towels, cooler Queen size sofa sleeper

Guesthouse in Urbana

4.95 out of 5 average rating, 230 reviews

West Urbana state street guest suite

Next to the heart of University of Illinois campus, surrounded by beautiful mature trees, this spacious and serene guest suite will enhance your experience in town. The guest suite has it own entrance. It is connected to the sunroom of our main house. This space do not come with TV, washer and dryer. And the space do not have kitchenette. However, we provide microwave, mini fridge, and coffee maker. This space is not limited mobility accessible. No party and no smoking.

Guesthouse in St. Louis

4.99 out of 5 average rating, 107 reviews

The PS Carriage House: Spa Tub + Walk Everywhere!

Located in the heart of Soulard, a dense STL neighborhood with a French Quarter vibe and the center of St. Louis' music scene, this historic two story carriage house is close to everything (WalkScore of 92/100). After enjoying the sights, unwind in the gated patio oasis or in the large spa tub upstairs. Just a half block to the famous Soulard farmer's market and to tons of bars/restaurants (most offer free shuttles to Cardinals, Blues, STL City, and Battlehawk games).

Guesthouse in Effingham

4.91 out of 5 average rating, 310 reviews

Country cottage tiny home.

This 240sq ft cottage offers big living in a tiny space. The cottage is on our 2 acre property that is used for a hobby farm and primary residence. The cottage features luxury vinyl flooring, granite counter tops and an updated farm house feel. The queen size bed is sure to provide the right amount of comfort. When you wake up, walk on over and grab a cup of coffee from the keurig. Enjoy a walk around to see the goats and chickens before heading off for the day.

Guesthouse in Iowa City

4.98 out of 5 average rating, 231 reviews

River Street Suite

Enjoy the beautiful Iowa River and Pennisula Park Views, in this private and peaceful guest suite apartment with private outdoor entrance and driveway. Walk to the Carver-Hawkeye Arena, Kinnick Stadium, UI Medical Campus & Veterans Hospital. Located in a highly sought-after walkable location off the Iowa River Corridor Trail. Less than a mile away from Hancher Auditorium & UI Campus. A 5 min drive to downtown Iowa City, Iowa River Landing Coralville and I-80.

Guesthouse in Crawfordsville

4.96 out of 5 average rating, 554 reviews

Mimi's Country Cottage

Quaint, quiet and cozy cottage set in a tranquil park like setting with all the amenities of home. Close to Shades and Turkey Run State Parks. A great place to stay for the Covered Bridge Festival. 15 minutes to Wabash College, 25 minutes to DePauw University, 45 minutes to Purdue. We live on site and our back door is approximately 600 ft. from from the Airbnb. PETS ARE NOT ALLOWED. We clean the cottage in accordance with CDC guidelines.

Guesthouse in Union

4.98 out of 5 average rating, 121 reviews

Route 66 Retreat - Bring your pets!

Our pet-friendly, peaceful pit stop is perfect for those traveling the Mother Road, heading to Missouri wine country, or exploring St. Louis area attractions like Purina Farms, Meramec Caverns and much more. This newly remodeled, rural retreat has all the amenities you need for a good night’s rest during a road trip or to spend a few days and relax. There is both indoor and outdoor space to enjoy, including a fenced in yard for pets.

Vacation rentals for every style

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Convenient locations with everyday essentials

Popular amenities for Central Illinois guesthouse rentals

Free parking on premises

Air conditioning

Family-friendly guest house rentals

Guesthouse in Marthasville

4.96 out of 5 average rating, 250 reviews

Hazel's House by the Katy Trail

Guesthouse in Hermann

4.99 out of 5 average rating, 128 reviews

Grapevine Guesthouse

Guesthouse in Kampsville

4.81 out of 5 average rating, 43 reviews

The Watkin's Place at McCully

Guesthouse in St. Louis

4.89 out of 5 average rating, 887 reviews

Unique Carriage House: Fun for the whole family!

Guesthouse in Urbana

4.97 out of 5 average rating, 420 reviews

Private Studio Loft for People, Pets, and Yoga

Guesthouse in Chesterton

4.92 out of 5 average rating, 345 reviews

"myhathouse" detached studio downtown Chesterton

Guesthouse in Miller Beach

4.17 out of 5 average rating, 29 reviews

Coach House, Dunes Nat’l Park, 10min hike to Beach

Guesthouse in Lane

4.71 out of 5 average rating, 140 reviews

Lane Place

Guest house rentals with a patio

Guesthouse in Merrillville

4.91 out of 5 average rating, 65 reviews

Guesthouse/ In-Law Suite with Jacuzzi/Sauna/Pool

Guesthouse in Urbana

4.92 out of 5 average rating, 73 reviews

Private Guest House Near Campus

Guesthouse in Carrollton

4.96 out of 5 average rating, 74 reviews

Shade Family Inn-Carrollton 2-bedroom Apt

Guesthouse in Quincy

4.98 out of 5 average rating, 50 reviews

Morgan Creek Carriage House

Guesthouse in Hannibal

4.92 out of 5 average rating, 37 reviews

Quiet/ Relaxing Little Studio

Guesthouse in Valparaiso

4.98 out of 5 average rating, 132 reviews

Cozy Luxe Downtown Valparaiso Stay

Guesthouse in Valparaiso

5 out of 5 average rating, 40 reviews

Lake retreat w/ unique dome near Indiana Dunes

Guesthouse in Hermann

5 out of 5 average rating, 96 reviews

Das Hundehaus-Downtown Location-Off Street Parking

Guest house rentals with a washer and dryer

Guesthouse in Carlyle

4.97 out of 5 average rating, 64 reviews

Cabin Near Carlyle Lake

Guesthouse in Mascoutah

4.97 out of 5 average rating, 213 reviews

The Carriage House

Guesthouse in Pittsfield

4.85 out of 5 average rating, 20 reviews

Private Guesthouse Kitchen Washer Dryer Dishwasher

Guesthouse in Yorkville

5 out of 5 average rating, 21 reviews

1 Bedroom Nature Retreat w/Hot Tub Close to Stores

Guesthouse in Iowa City

4.97 out of 5 average rating, 36 reviews

Carriage House Guest Home, Peninsula Neighborhood

Guesthouse in Union

5 out of 5 average rating, 27 reviews

Adorable three bedroom guest house with patio

Guesthouse in St. Peters

4.96 out of 5 average rating, 54 reviews

Maple Tree Enchanted Guest House 1 bedroom 2 beds

Guesthouse in Union

4.95 out of 5 average rating, 152 reviews

Dog Friendly One Bedroom Guest House

Destinations to explore