Vacation rentals in DeSoto County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in DeSoto County

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Home in Southaven

4.9 out of 5 average rating, 41 reviews

Large Groups & Special Occasions!

Enjoy our spacious home and friendly community. Sleeping for over 20 guests, a gym, office, recreation areas, and expansive driveway, perfect for short or long stays and groups of all sizes. Plans for over 40 visitors or large outdoor activities require an additional accommodation fee. We request the garage remain closed during mandated 10 PM outdoor quiet hours. No guns or smoke inside. No vehicles on grass. Near: *Tanger Outlets~5min *Landers Center~6min *MEM Airport~17min *Beale Street~22min

Guest favorite

Home in Hernando

4.89 out of 5 average rating, 226 reviews

Hernando Hideaway (Entire Lakehouse)

Enjoy our 2000 sq ft lake house in a private peaceful community with panoramic views of the lake. We are a licensed BNB with DeSoto County and the State of Mississippi until the year 2035. (Lic # 20110070) You will have the entire lake house to yourself and we provide coffee and pastries for breakfast. We are 15 minutes from Tunica Expo, 5 minutes to Tunica National Golf Course, 10 Minutes to the casinos; 38 minutes to Beale St, Bass Pro Shop, Peabody Hotel, Graceland and The Lorraine Hotel.

Superhost

Home in Southaven

4.79 out of 5 average rating, 48 reviews

Townhouse near by everything! 10% off at my salon!

Have fun with the whole family at this stylish place. Near by almost everything you need to do in Southaven and Memphis. You will be close to Tanger Outlet, developing Silo Squares, different restaurants within 1 or 2 miles. You will stay only 15 minutes away from the Airport, and If you want to visit Graceland, downtown Memphis but you don’t want to stay in Memphis, give my spot a try. Besides the staying, you will have 10% off of any services at my salon😊. I can’t wait to serve you all!

Guest favorite

Guesthouse in Hernando

4.98 out of 5 average rating, 159 reviews

Guesthouse 1 bed, beautiful views NO cleaning fees

Adorable 1 bedroom quite hide-a-way, but still have the convenience of being located close to everything. There are beautiful views from the front covered porch. NO PARTIES! Located about 20 minutes from Memphis and Tunica Casino Strip. Enjoy local attractions: Hernando Town Square, Snowden Grove, Shopping, Graceland, Memphis Botanic Gardens, Museums and Beale Street. This area and home is made for family life, not for the party style, come and enjoy your tranquil stay with us.

Superhost

Home in Southaven

4.86 out of 5 average rating, 50 reviews

The Country Cottage

Escape to the tranquility of our charming country cottage in Southaven, MS! Nestled on private farmland, this hidden gem offers the perfect retreat. Enjoy the best of both worlds with a serene countryside setting and easy access to modern amenities. Only a 5-10 minute drive away, you'll find the Landers Center for events, the Tanger Outlet Mall for shopping, and quick access to Interstate 55 for your convenience. Book your stay today and create lasting memories at our Southaven oasis.

Guest favorite

Home in Olive Branch

5 out of 5 average rating, 15 reviews

Pleasant Hill Estate

Welcome to our unique and stylish home, nestled in a serene environment. With thoughtful amenities & a warm ambiance, you’ll never regret choosing to stay here. The property features elegant architectural design with natural stones, providing a harmonious blend of elegance and natural beauty. The well-maintained exterior, with a beautiful lake and inviting landscaping, adds to the overall appeal of the 8-acre land with oak and magnolia trees. Book your unforgettable experience today!

Guest favorite

Guesthouse in Hernando

5 out of 5 average rating, 105 reviews

Cozy 2 Bedroom Guesthouse in a Relaxing Setting

Our two bedroom, two bath guesthouse is the perfect get-a-way from it all, yet close enough to everything you're looking to do: 3 minutes to the historic Hernando Town Square, 10 minutes to the MS River Delta and Historic Hwy 61, 12 minutes to Tanger Outlets & Landers Center in Southaven, 20 minutes to Snowden Grove Ballfields & Amphitheatre in Southaven, 23 minutes to Tunica Casino Strip, 25 minutes to Midtown/Downtown Memphis, 1 hour to Oxford, MS and 1 hour to Clarksdale, MS.

Guest favorite

Home in Hernando

5 out of 5 average rating, 24 reviews

Studio Downtown! Clean, great location, sleeps 4!

Enjoy a stylish modern experience at Studio Downtown! Featuring 1 king bed and queen size sofa bed. Galley kitchen w/Keurig coffee machine, microwave, range and refrigerator. Full bathroom with walk in double shower. Laundry room with washer and dryer. Smart 65” tv and Wi-Fi. Very safe location in the historic district of downtown Hernando. Enjoy the multiple outdoor seating areas and corn hole boards. Within walking distance to restaurants and the town square. Owner/Agent.

Guest favorite

Farm stay in Southaven

4.99 out of 5 average rating, 90 reviews

“The Longhorn House” at Blue Haze Farms

Get away from it all when you stay under the stars at our rustic tiny house. Kayak the lake or just take a hike. Sink into the memory foam mattress with luxurious linens and watch a movie on one of the smart TVs. Listen to some of our vintage records or play some old fashion board games ! Just want to relax? Curl up in the swing chair and watch our miniature Longhorns graze. Conveniently located south of Memphis, TN & Graceland. Relax. Unwind. Rejuvenate.

Guest favorite

Farm stay in Olive Branch

4.97 out of 5 average rating, 332 reviews

Horse Farm Hideaway

Industrial farmhouse style meets southern charm on an idyllic horse boarding family farm safely outside of Memphis. Perfect location both for sightseeing in Memphis or bypassing the city entirely. Take a walk among the horses, pigs, chickens, ducks, and other wildlife to decompress. Full kitchen and a large bathroom. Guests sleep well in our quiet and private space. Due to large animals and farm machinery, our place is not suitable for children under 12.

Guest favorite

Home in Southaven

4.94 out of 5 average rating, 50 reviews

KING Bed -3 BD 3 Bth Spacious Hidden Gem!

Welcome to your perfect home away from home in Southaven, Mississippi! This beautifully appointed 2-story home is the ideal retreat for families and groups seeking comfort, convenience, and an unforgettable stay in this charming southern city. The home also offers convenient parking in the luxury 2-car garage and within one or two minutes to Hwy 51 and I-55, making it a perfect base for exploring the vibrant city of Southaven and its surrounding areas.

Guest favorite

Guesthouse in DeSoto County

4.91 out of 5 average rating, 58 reviews

Bonne Terre Cottage Room

Relaxing private upstairs room in a building to yourself. Located in Nesbit, MS: Fantastic stay for the Blues Trail, Memphis, Oxford, or Snowden Grove *20 min from downtown Memphis, Memphis Airport, and Graceland* Perfect spot right outside the city to feel safe and secluded. This room is the UPSTAIRS of our cottage that has it's own private entrance. The downstairs is not used as a room, so no need to worry about sound.