Guesthouse vacation rentals in Durham

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Top-rated guesthouse rentals in Durham

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Guest favorite

Guesthouse in Fuquay Varina

4.95 out of 5 average rating, 228 reviews

Carriage House at Bracken in Downtown Location

New, private and quiet colonial Carriage House overlooking a park in historic downtown Fuquay-Varina. A lovely half mile walk to both Fuquay and Varina town centers with easy access to eateries, breweries and boutiques. Kitchen has full fridge, microwave, toaster oven, sink, 2 burner cooktop, Keurig with milk frother, coffee and tea supplies, cooking utensils, pots, pans, silverware, breakfast table and chairs. Our place has a queen bed, antique tall boy dresser, oak rocking chair, couch, and TV

Guest favorite

Guesthouse in Hillsborough

4.95 out of 5 average rating, 224 reviews

The Store in Hobo, a reader/writer’s retreat.

The Store in Hobo: a dog friendly reader/writer’s retreat in a renovated general store. Formerly “Paul’s Grocery” from 1943-73, the Store is on the Bellevue Mill Circle hilltop, an eclectic neighborhood bordering historic downtown Hillsborough. Whether you’re coming alone, with a friend or a small family, this comfy space will inspire creativity and provide serenity. Need room for 2 more? See The Mill House in Hobo on AirBnB. On the same property and with kitchen. (No dogs in Mill House)

Guest favorite

Guesthouse in Hillsborough

4.97 out of 5 average rating, 195 reviews

CFCB cabin retreat minutes from Duke, NCCU, & UNC

Cozy, wheelchair-accessible, recently renovated cabin with unique decor and a sitting porch, located in a beautiful, mature, piedmont forest that abounds with wildlife and has hiking trails along New Hope Creek. Ideal for a quiet retreat but only 8 minutes from UNC Hospital, Hillsborough Campus and within 15 to 25 minutes from Duke University, University of North Carolina at Chapel Hill, North Carolina Central University and historic downtown Hillsborough. Guests of all walks of life welcome.

Guest favorite

Guesthouse in Durham

4.94 out of 5 average rating, 251 reviews

Modern Cottage With a Vintage Twist Near Downtown

Come stay at our modern vintage guesthouse in Historic Trinity Park. Our cottage has all modern appliances with vintage fixtures. This 380 square foot cottage is located in a very lively and safe neighborhood just minutes from downtown Durham. Walk one mile on the Ellerbe creek trail to downtown and enjoy all the great entertainment Durham has to offer. Walk 1.5 mile to 9th street restaurants and shops 1 mile to Central Park and farmers market <1 mile to bars and restaurants on geer street

Guest favorite

Guesthouse in Durham

5.0 out of 5 average rating, 359 reviews

Light-filled Guesthouse Near Duke

Best of both worlds--a new garage apartment in a charming, peaceful Durham neighborhood. Twenty minutes to RDU Airport, five minutes to Duke's East Campus and ten minutes to West Campus, we are an easy walk to a range of locally-owned restaurants. Lovely, light-filled apartment has a bedroom, full kitchen and living area, bathroom, private entrance, and patio with seating. Occasionally, we may have first-floor space available at extra cost. Well-behaved pets welcome. See below for fees.

Guest favorite

Guesthouse in Saxapahaw

4.92 out of 5 average rating, 702 reviews

The Yurt at Frog Pond Farm

Our yurt (30' dia.) is rustic, beautiful, quiet, in deep woods with deck overlooking pond. Great for couples, small families (not childproof). Includes hot tub & Poetry Walk. Beds are futons. It's warm June-Aug. (no A/C, plenty fans), but way cooler than the city. It's cold Nov.-March (wood stove heat). Mini-fridge & microwave (no kitchen/plumbing). Bath-house is 2-min. walk (toilet, sink, shower). Two minutes to Saxapahaw. Read description for more info. SERIOUSLY NO PARTIES. And no dogs.

Guest favorite

Guesthouse in Durham

4.95 out of 5 average rating, 120 reviews

Spotless Scent & Mold-Free Guesthouse Near Duke!

New-construction (2022) spotlessly clean farmhouse-style guesthouse is 3 mins to Duke, 15 mins to UNC and 25 mins to Raleigh. Perfect for an RTP work trip or weekend alumni or family/student visit. Explore Durham (8 min drive to downtown Durham, DPAC, American Tobacco, etc.) or anywhere in the Triangle from this South Durham location in the charming Tuscaloosa-Lakewood neighborhood. Walking distance to Cocoa Cinnamon coffee shop and restaurants serving breakfast, lunch and dinner.

Guest favorite

Guesthouse in Hillsborough

4.96 out of 5 average rating, 336 reviews

Hummingbird Retreat

Airy and open, private and quiet! Come get away from it all and still be a short drive to all that the Triangle has to offer! High quality cottage style carriage house loft with full bath & private entrance - luxurious king-sized bed, Bonavita coffee maker, and handy microwave and mini fridge. Located just 4 miles south of hip and historic downtown Hillsborough in a rural, wooded country setting. Close access to Duke, UNC Chapel Hill; and Elon University is 27 miles west on I40.

Guest favorite

Guesthouse in Raleigh

4.95 out of 5 average rating, 249 reviews

Raleigh Oasis Close to it All

The pool is OPEN. Pack your swimsuit! Construction Discount in effect (see the Guest Safety section below) An owner-occupied private residence with a large pool and guesthouse above the detached garage. Enjoy the sights and sounds of a stocked koi pond or observe nature from the private balcony. Minutes from Rex Hospital, Crabtree Mall, Art Museum and PNC arena, the location cannot be beat. Feel far from the city while close to all of the things Raleigh/Durham have to offer.

Guest favorite

Guesthouse in Cary

4.99 out of 5 average rating, 271 reviews

Cary Downtown on the Park Studio Loft

In Cary's Cultural Arts District. BEST LOCATION IN CARY!!! ON THE NEW DOWNTOWN PARK. Amongst many eateries, pubs, venues, etc. See photos & Guide Book in listing. Quiet loft studio modern design, construction in separate building away from busy-noisy streets. On quaint alley w/ parking. Located directly across from new $65M park. BEST LOCATION IN THE RALEIGH- DURHAM AREA. 15 mins. to airport, RTP, Raleigh, NC State, PNC Arena. 30 mins. to Duke, Durham, UNC Chapel Hill.

Guest favorite

Guesthouse in Chapel Hill

4.96 out of 5 average rating, 342 reviews

Cozy Secluded Accessible West Wing

The West Wing is guest quarters to a residence on 15 acres 5 miles south of Chapel Hill. It's an easy 10 minutes (5 miles) to downtown Chapel Hill, UNC, UNC Hospitals and Carrboro. Comfortable, clean, attractive, and very secluded. It is a studio apartment with one double bed, perfect for one person, cozy for two.. Your friendly, well behaved dog is welcome, but don't ever let your dog on the furniture or leave your dog alone uncrated. Sorry, no cats.

Guest favorite

Guesthouse in Durham

4.96 out of 5 average rating, 805 reviews

Tiny House in the Trees

You'll sleep in a loft nestled in the trees, and wake up to the songs of the morning birds. Super comfy and whimsical, the tiny house has everything you'll need in 120 TINY square feet of charm, right in our backyard in case you need anything at all. The space can accommodate a max of two guests. * This cozy spot is for folks who like it simple, small, rustic and sweet. * * Intentionally, there are no window coverings except for on the kitchen window.*

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Durham guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

Guest favorite

Guesthouse in Raleigh

4.87 out of 5 average rating, 435 reviews

Adorable 1BR studio in Five Points

Guest favorite

Guesthouse in Cary

4.92 out of 5 average rating, 296 reviews

Central to Everything, Renovated, Dog Friendly.

Guest favorite

Guesthouse in Raleigh

4.98 out of 5 average rating, 894 reviews

Walk to downtown. Private stylish studio cottage.

Guest favorite

Guesthouse in Apex

4.92 out of 5 average rating, 350 reviews

Country place close to all Triangle locations

Guest favorite

Guesthouse in Carrboro

4.85 out of 5 average rating, 413 reviews

Guest cottage close to downtown Carrboro

Guesthouse in Durham

4.87 out of 5 average rating, 181 reviews

Rockwood Oasis Studio BR Bath no kitchen

Guesthouse in Raleigh

4.84 out of 5 average rating, 95 reviews

Peaceful guest house near downtown Raleigh

Guest favorite

Guesthouse in Raleigh

4.98 out of 5 average rating, 90 reviews

Charming Cottage House in Historic Raleigh

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Guest house rentals with a patio

Guest favorite

Guesthouse in Raleigh

4.9 out of 5 average rating, 124 reviews

Retreat La Cabana

Guest favorite

Guesthouse in Raleigh

4.99 out of 5 average rating, 134 reviews

Downtown Private Oasis w/ Cal King

Guest favorite

Guesthouse in Durham

5.0 out of 5 average rating, 9 reviews

New Apt- walk to everything Rockwood

Guest favorite

Guesthouse in Durham

4.98 out of 5 average rating, 85 reviews

Great Guesthouse Studio Suite w/ hot tub & pool!

Guest favorite

Guesthouse in Durham

5.0 out of 5 average rating, 19 reviews

“Meelie Doll”~ Private - Cozy Stdio Apt abv garage

Guest favorite

Guesthouse in Chapel Hill

4.9 out of 5 average rating, 52 reviews

The cozy home

Guest favorite

Guesthouse in Raleigh

5.0 out of 5 average rating, 28 reviews

Carriage House Studio in Quiet Neighborhood

Guest favorite

Guesthouse in Holly Springs

5.0 out of 5 average rating, 86 reviews

"Wit's End" welcomes you! 2BR comfy guest house

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Guest house rentals with a washer and dryer

Guest favorite

Guesthouse in Cary

5.0 out of 5 average rating, 113 reviews

Guest House on the Cary Downtown Park!

Guest favorite

Guesthouse in Wake Forest

5.0 out of 5 average rating, 136 reviews

2 BR, 1.5 BA Guest House on 2-acre wooded lot

Guest favorite

Guesthouse in Raleigh

4.95 out of 5 average rating, 133 reviews

Changes In Latitudes Pool & Suite Raleigh NC.

Guest favorite

Guesthouse in Raleigh

4.99 out of 5 average rating, 137 reviews

Modern Retreat near Downtown Raleigh

Guest favorite

Guesthouse in Durham

5.0 out of 5 average rating, 53 reviews

Delightfully Durham: Guesthouse with Kitchen!

Guest favorite

Guesthouse in Durham

4.93 out of 5 average rating, 43 reviews

Duplex filled with natural light

Superhost

Guesthouse in Durham

4.91 out of 5 average rating, 91 reviews

Adorable + private guesthouse close to downtown

Guest favorite

Guesthouse in Durham

4.97 out of 5 average rating, 35 reviews

DownUnder @DukePark Standing Desk Charming & Clean

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Quick stats about guesthouse rentals in Durham

Total rentals
40 properties
Local attractions
Brier Creek Commons, Durham Bulls Athletic Park, and American Tobacco Campus
Popular amenities
Kitchen, Wifi, and Pool
Wifi availability
40 properties include access to wifi
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Total number of reviews
3.9K reviews

Guesthouse vacation rentals in Durham

Top-rated guesthouse rentals in Durham

Vacation rentals for every style

Houses

Apartments

Cabins

Popular amenities for Durham guesthouse rentals

Family-friendly guest house rentals

Guesthouse in Raleigh

Guesthouse in Cary

Guesthouse in Raleigh

Guesthouse in Apex

Guesthouse in Carrboro

Guesthouse in Durham

Guesthouse in Raleigh

Guesthouse in Raleigh

Guest house rentals with a patio

Guesthouse in Raleigh

Guesthouse in Raleigh

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Chapel Hill

Guesthouse in Raleigh

Guesthouse in Holly Springs

Guest house rentals with a washer and dryer

Guesthouse in Cary

Guesthouse in Wake Forest

Guesthouse in Raleigh

Guesthouse in Raleigh

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Durham

Guesthouse in Durham

Quick stats about guesthouse rentals in Durham

Total rentals

Local attractions

Popular amenities

Wifi availability

Rentals with dedicated workspaces

Total number of reviews

Destinations to explore