House vacation rentals in East County, San Diego

Find and book unique houses on Airbnb

Top-rated house rentals in East County, San Diego

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in Julian

4.99 out of 5 average rating, 106 reviews

Maison Zen

Nestled high on the hill, this private, cozy mountain sanctuary offers breathtaking views of Lake Cuyamaca and majestic Stonewall Peak. Enter the door of our serene and peaceful zen home and feel your entire body relax in the calming space. The floor-to-ceiling sliding glass doors open to a deck where you can enjoy a morning coffee, an evening glass of wine or a restorative yoga session. Maison Zen is ideal for a couple's getaway or an individual's "escape." Not suitable for children or infants.

Guest favorite

Home in La Mesa

4.9 out of 5 average rating, 163 reviews

Classic Mid-Century Mount Helix Home with Views

Located in the exclusive Mount Helix neighborhood of La Mesa, this property is conveniently located near the 8 and 94 freeways for easy access to explore the greater San Diego area. Attractions like the historic Balboa Park with the San Diego Zoo or Sea World are a 15-25 minute drive away. With spacious interior and exterior spaces at the property, though you may find it difficult to leave. The property includes 4 bedrooms and 2.5 bathrooms with furnished living room, family room and kitchen.

Guest favorite

Home in Alpine

4.94 out of 5 average rating, 156 reviews

Modern 2BR Farmhouse Retreat Family Friendly Stay

Welcome to the serene Mariposa Farmhouse, thoughtfully remodeled for your comfort. The moment you step inside, our aim is to make you feel at ease and right at home. Pets and families are always welcome! Start your mornings with a cup of coffee from our complimentary coffee bar, taking in the stunning mountain and desert views of the Cleveland National Forest from the master balcony. As night falls, unwind by the fire beneath a blanket of stars. We’re just 30 minutes to downtown and beaches.

Superhost

Home in La Mesa

4.86 out of 5 average rating, 206 reviews

Newer "Manor Studio"

Centrally located in San Diego County this brand new studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

Guest favorite

Home in Julian

4.96 out of 5 average rating, 143 reviews

Secluded Mountain Escape w/ Hot Tub & Scenic Views

Escape to this BRAND NEW renovated 1 bed/1 bath retreat in Julian, CA. Just minutes from town, enjoy local shops, wineries, and hiking trails with stunning views. Inside, relax in the cozy living room, cook in the fully equipped kitchen, work in nature and unwind! Unwind in the spacious bedroom with a plush king bed, or step onto the private deck to soak in the hot tub, stargaze, or savor your morning coffee. A perfect place to relax, recharge, reconnect & experience the magic of Julian!

Guest favorite

Home in Ramona

4.98 out of 5 average rating, 789 reviews

The Glass House - A Nature Retreat

Enjoy a unique retreat; 180 degrees of views from inside the home. Nestled at the end of a private road, our place is nearby great hiking and countryside wineries. The Glass House provides a magical space and nature retreat where individuals, couples, families and friends can gather together to re-connect with nature, each other, and themselves. The breathtaking mountain top views, the huge deck, hot tub, fireplace, and the open concept living space is unbeatable for the perfect getaway.

Guest favorite

Home in La Mesa

4.93 out of 5 average rating, 203 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Guest favorite

Home in La Mesa

4.99 out of 5 average rating, 188 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Guest favorite

Home in Alpine

4.99 out of 5 average rating, 174 reviews

Fully Fenced Alpine Property with Guest House

Our guest house is located in the back of our personal property & kept private by fencing. Our property is fully fenced & guests have access in & out by using a keypad. We have laundry facilities, a queen size bed in the master bedroom, a sofa sleeper in the living room/kitchen area and a private patio with bbq. We occupy the main home on the property. We have 2 dogs on the property so other animals are not recommended at this location. Children trampoline not included with Airbnb.

Guest favorite

Home in Alpine

5 out of 5 average rating, 110 reviews

New Country House - Self Check In & Dog Friendly

Come and enjoy tranquility with all the comforts of home in our new country style house. Relax with all the luxuries of home. Private, quiet and yet only 5 minutes from the freeway. Enjoy hiking, biking, shopping, great restaurants even gambling within minutes away. Also enjoy being 30 minutes from Sea World, The San Diego Zoo and beaches. We are also close to Julian and Cuyamaca Lake. Great for small families or a small group of friends to just get away from it all and relax.

Guest favorite

Home in La Mesa

4.88 out of 5 average rating, 157 reviews

The Queen House

Bring your whole family to our beautiful Endless Summer home with 4 bedroom, 2.5 bath. Our home is located 15 mins from Downtown San Diego, Petco Park, San Diego Zoo, Convention Center, Beautiful Local Beaches, shopping and more. We live in the area of La Mesa called Mount Helix. Our home has been newly remodeled and offers each guest a unique experience. With our gorgeous canyon and international views, a swimming pool and waterfall, you won't find another home like it.

Guest favorite

Home in Spring Valley

4.83 out of 5 average rating, 255 reviews

ROMANTIC AND SPACIOUS JACUZZI SUITE!

Completely private sanctuary--no shared spaces--and it has a private entrance. Enjoy stunning sunrises and sunsets from your two private balconies. Unwind in the jacuzzi. This suite is provided with everything you need to feel at home, such as plush mattresses and linens, a kitchenette with microwave, coffee maker, mini-frig, toaster, and necessities including silverware and dishes, and in the bathroom, an iron and hair dryer.