Boutique hotel vacation rentals in Gulf of Mexico

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Gulf of Mexico

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Hotel room in La Habana

5 out of 5 average rating, 103 reviews

Comfort private room, El Vedado, Havana

Are you traveling solo, as a couple, or with friends? Then “stop looking”, you’ve already found your home base while in Havana. Large private ensuite rooms with comfortable beds; fitted with flat TV, ceiling fan, AC, mini-fridge and security boxes. Wi-Fi included. Ideal location to catch a taxi or the tour bus (crossing the street); a short cab rides away (8 min) from Old Havana; restaurants, bars and cafes everywhere in a quiet and safe neighborhood (El Vedado) just steps away from the Malecon.

Guest favorite

Hotel room in Galveston

4.88 out of 5 average rating, 625 reviews

Tropicana Suite-Grand Manor Luxury Mansion Loft

The elegant Grand Manor, built in 1905, a true southern tropical mansion. Luxurious amenities seamlessly blended with Victorian grace. Located in Galveston's East End Historic District & is considered one of the top architectural structures on the Island.Guest rooms are richly appointed, with king size beds. Private baths are Jacuzzi or claw-footed tubs. Best walking location B&B on Island . The beach,Funky bars & rooftop patios minutes away at WORLD FAMOUS STRAND . (2 other rooms available)

Guest favorite

Hotel room in Galveston

4.94 out of 5 average rating, 404 reviews

Rm 3 @ St. Helen's House Hotel (Cruise Terminal)

This is a double room with a newly built private ensuite bathroom with shower. Saint Helen's House is a quaint boutique hotel in the heart Galveston's East End Historic District. It has multiple guest rooms and shared common areas with plenty of space to socialize or be alone. The Hideaway is a large Victorian era home located on the north side of broadway just a half mile from downtown and UTMB. Linens, fresh towels, coffee & water are provided. A fully equipped kitchen is shared by guests.

Superhost

Hotel room in Mérida

4.84 out of 5 average rating, 431 reviews

Suite Pool View @hotelitoyumkaax Mérida, Centro

Welcome to Hotelito Yum Kaxx, your very own OASIS! Just a few blocks from Plaza Grande, right in the heart of it all...and suddenly, you stumble upon our secret haven. Our place is more than just a place to lay your head; it's like discovering a unicorn in the heart of the city. A magical spot where the laid-back vibes embrace you the moment you step through the door. Ready to dive into this slice of peaceful paradise in Mérida Centro? Book now and get ready for an unforgettable experience!

Guest favorite

Hotel room in Ocean Springs

5 out of 5 average rating, 142 reviews

Mocking Bird Inn- Willow Suite

*PERFECT LOCATION* Built in 1899 and newly renovated, The Mocking Bird Inn- Willow Suite is nestled on a LIVE OAK lined historic street. This home is a true southern charmer! FORT BAYOU is located next to the property. Take a stroll next door to MARBLE SPRINGS PARK for a view of the bayou and learn the history of the NATURAL SPRINGS that gave OCEAN SPRINGS its name. Just 1 block to DOWNTOWN OS GALLERIES, SHOPPING & RESTAURANTS , 1 mile to the BEACH, 2 miles to CASINO's

Guest favorite

Hotel room in Havana

4.93 out of 5 average rating, 139 reviews

CRISTAL -Portería - My Proud Havana

High standard room on a classical house of the 1950s in Vedado neighborhood, few blocks to Line and 23th Ave, perfect connection to the whole city. Original paintings and exquisite taste original furnitures too. You will have a unique high standard experience comparable to 5 star hotels in Havana. With AC, Coffee Maker.MASSAGE ROOM. We also offer breakfast service the a cost is 6 euros per person per day. internet access through cards, free during breakfast hours

Guest favorite

Hotel room in Old Havana

4.89 out of 5 average rating, 511 reviews

Casa Habana Vieja, an special place

In this boutique house recently restored , you can enjoy a spacious living room, kitchen, bathroom, terrace, two bedrooms and a balcony overlooking the historic center. Just a few meters from the Loma del Angel, artists alley, against a beautiful bohemian restaurant; offers a unique atmosphere of comfort. Another of our houses you can see: - Casa Medina, a happy stay - Casa Medina Centro Habana - Casa Janhna - Casa Habana Vieja, a place to remember

Superhost

Hotel room in Key West

4.88 out of 5 average rating, 394 reviews

Mallory House Room #3

There is no better place for your Key West stay than Mallory House. This historic circa 1890’s home is located on Duval Street in the Gato Cigar Factory Village. Mallory House is steps away from famous attractions, restaurants, cafés, bars and shops. Stay within close proximity to the Southernmost point and beach, the Hemingway house and lighthouse. Enjoy a complimentary cup of coffee on our spacious balcony overlooking world famous Duval Street.

Guest favorite

Hotel room in La Habana

4.98 out of 5 average rating, 135 reviews

Balconies of Cuba, 20mt from Bodeguita del Medio.

"Balcones de Cuba" is located in the historic center of Old Havana, 20 meters from the famous Bar-Restaurant "La Bodeguita del Medio". It is a colonial house, built in 1925, horizontal property, with 5 meters high ceilings and colorful mosaics of the time, very bright and ventilated, because it is on a third and last level of a magnificent building. Its current owners are the second owners,who restructured it maintaining every detail of the time.

Superhost

Hotel room in Isla Mujeres

4.87 out of 5 average rating, 151 reviews

King Suite - Icaco Island Village

The King Suite at Icaco Island Village - Adults Only features a convienient in-room kitchenette with access to the roof-top communal kitchen and BBQ station. The room also has a stunning balcony overlooking the crystal clear blue waters of the carribean. Free parking for golf carts and quads located on site. Cool off in the rooftop infinity pool featuring breathtaking 360 degree views of this beautiful island. In Paradise We Trust.

Superhost

Hotel room in Angleton

4.87 out of 5 average rating, 119 reviews

The Gayle Suite @ 116B

Newly renovated Historic downtown suite located above the restaurant & music venue, The Dirty South, situated 2 blocks from the Brazoria County court house. Suite includes a small living room with fold out couch and TV with Cable and YouTube TV, Kitchen/dining with seating & mini fridge, and king sized bedroom with top of the line linens and mattress. Bathroom includes walk in shower with updated tile, fixtures & ample lighting.

Superhost

Hotel room in Saint George Island

4.84 out of 5 average rating, 269 reviews

Island Suites - Room 8 - 1 King Bed

The Island Suites is located on St. George Island on the beach front within walking distance to the majority of restaurants and shops. Each room has a private balcony overlooking the Gulf of Mexico, 1 king or 2 queen beds, refrigerator, microwave, in-room coffee, guest room amenities, cable and internet. When making your reservation please note there are 8 different rooms so if one is not available scroll through the others.