Guesthouse vacation rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mesa
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesa guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Gilbert
4.99 out of 5 average rating, 224 reviewsTnT Family Farm Guest House
Guesthouse in Paradise Valley Village
4.96 out of 5 average rating, 145 reviewsCozy Guest Home away from Home
Guesthouse in Ahwatukee Foothills
4.98 out of 5 average rating, 898 reviewsBoutique Hotel Style Guest House
Guesthouse in Paradise Valley Village
4.9 out of 5 average rating, 623 reviewsScottsdale guest suite
Guesthouse in Camelback East
4.97 out of 5 average rating, 414 reviewsThe Cozy Container with pool & gym
Guesthouse in Downtown Phoenix
4.98 out of 5 average rating, 199 reviewsExplore Downtown Phoenix from a Spanish-Style Retreat
Guesthouse in Camelback East
4.87 out of 5 average rating, 491 reviewsArchitectural Dream Guest House
Guesthouse in Central City
4.97 out of 5 average rating, 177 reviewsDowntown Phoenix Neighborhood Guest House.
Guest house rentals with a patio
Guesthouse in Glendale
4.85 out of 5 average rating, 188 reviewsLuxe Tiny Cottage Home in Historic Glendale
Guesthouse in Glendale
4.94 out of 5 average rating, 157 reviewsOrchard House Cozy Pool Casita
Guesthouse in Central City
4.83 out of 5 average rating, 175 reviewsEntire Guest House Near Downtown Phoenix
Guesthouse in Camelback East
4.97 out of 5 average rating, 145 reviewsSimple, Clean, Convenient Casita. Private, safe.
Guesthouse in Apache Junction
5 out of 5 average rating, 43 reviewsGoldfield View Cottage
Guesthouse in Gilbert
4.81 out of 5 average rating, 27 reviewsSecluded and ADA accessible.
Guesthouse in Scottsdale
4.98 out of 5 average rating, 85 reviewsEntire Private Guest House with King Master
Guesthouse in Tempe
4.75 out of 5 average rating, 24 reviewsAdorable guest house with a pool
Guest house rentals with a washer and dryer
Guesthouse in Mesa
4.99 out of 5 average rating, 177 reviewsHideaway- Pool, Hot tub, Bikes, Near Hiking, Lakes
Guesthouse in Encanto
4.99 out of 5 average rating, 122 reviewsCASA OBSCURA | private, modern spanish casita
Guesthouse in Camelback East
4.9 out of 5 average rating, 136 reviewsHubbell Hideaway Main House Near Downtown Phoenix
Guesthouse in South Mountain
4.93 out of 5 average rating, 276 reviewsBrand New Casita at South Mountain
Guesthouse in Tempe
4.94 out of 5 average rating, 129 reviewsArtist Studio Turned Colorful Casita in the Heart of Tempe
Guesthouse in Central City
4.84 out of 5 average rating, 128 reviewsAdorable one bedroom guest house with parking
Guesthouse in Fountain Hills
5 out of 5 average rating, 10 reviewsYour own little home- La Casita of Fountain Hills
Guesthouse in Camelback East
4.93 out of 5 average rating, 88 reviewsBright & Beautiful Guesthouse, add on pool access
Quick stats about guesthouse rentals in Mesa
Total rentals
120 properties
Nightly prices starting at
$40 before taxes and fees
Total number of reviews
8.1K reviews
Family-friendly rentals
20 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with a pool
40 properties have a pool
Destinations to explore
- Tucson Vacation rentals
- Scottsdale Vacation rentals
- Tempe Vacation rentals
- Mount Lemmon Vacation rentals
- Chandler Vacation rentals
- Glendale Vacation rentals
- Gilbert Vacation rentals
- Palm Springs Vacation rentals
- Joshua Tree Vacation rentals
- Las Vegas Vacation rentals
- Las Vegas Strip Vacation rentals
- Phoenix Vacation rentals
- House rentals United States
- Guesthouse rentals United States
- Guesthouse rentals Phoenix
- House rentals Phoenix
- House rentals Tucson
- Guesthouse rentals Tucson
- Serviced apartment rentals Mesa
- Family-friendly rentals Mesa
- Fitness-friendly rentals Mesa
- Rentals with a kayak Mesa
- Rentals with pools Mesa
- Pet-friendly rentals Mesa
- Monthly Rentals Mesa
- Villa rentals Mesa
- Kid-friendly rentals Mesa
- Private suite rentals Mesa
- Rentals with a sauna Mesa
- Rentals with a fire pit Mesa
- Resort rentals Mesa
- Rentals with breakfast Mesa
- Rentals with an accessible height toilet Mesa
- Townhouse rentals Mesa
- Waterfront rentals Mesa
- Rentals with a home theater Mesa
- Rentals with an EV charger Mesa
- Smoking-friendly rentals Mesa
- Rentals with lake access Mesa
- Condo rentals Mesa
- Rentals with a hot tub Mesa
- Rentals with a patio Mesa
- Ski-in/ski-out rentals Mesa
- Rentals with a fireplace Mesa
- House rentals Mesa
- Apartment rentals Mesa
- Rentals with a washer and dryer Mesa
- Rentals with outdoor seating Mesa
- Guesthouse rentals Scottsdale
- House rentals Scottsdale
- House rentals Arizona
- Guesthouse rentals Arizona
- House rentals Maricopa County
- Guesthouse rentals Maricopa County
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom