Vacation rentals in Perry County

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Top-rated vacation rentals in Perry County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Farm stay in Frohna

4.98 out of 5 average rating, 117 reviews

The Weber Farm - Enjoy a beautiful 100 acre farm!

Enjoy a 125+ year old country home with large yard and beautiful shade trees located on a 100-acre farm in the rolling hills of SE Missouri. The house is very clean and spacious with 4 large bedrooms, comfortable beds, beautiful hardwood floors and a large living room. We have hand-made quilts and antique furniture throughout. The kitchen is fully furnished. Relax on our 40’ front porch with swing, by the fire pit or in a hammock. A perfect place for you to recharge from stress & busy schedules!

Guest favorite

Home in Ava

4.91 out of 5 average rating, 89 reviews

JGB’s Farm and Getaway

We are in the country next to a blacktop road.This is a very laidback place , there are farm animals across the road at our farm. This was my moms farm house and I just want people to enjoy it as much as she did. We are close to Kincaid Lake, the local winerie, the World Shooting Complex, and hiking trails (Piney Creek Revenue). Come and enjoy a day fishing or just sitting on the back deck enjoying the peaceful surroundings. Later build a fire and sit back and relax. Come and enjoy the country.

Guest favorite

Loft in Perryville

4.97 out of 5 average rating, 298 reviews

Downtown Loft Amazing Bath Tub & Shower

Downtown Perryville, MO **DISCLAIMER** you will hear restaurant chatter & music if you do not have a tv/or radio playing between the hours of 10:30am & 1:30am. If you go to bed early I recommend headphones, ear plugs or play nature sounds on Alexa. This is a pet friendly loft apartment so I would not recommend if you are allergic to dogs or cats. This apartment is located above one of the most popular destination restaurant's around "Mary Jane Burgers & Brew" on the Downtown Historic Square.

Guest favorite

Dome in Perryville

4.94 out of 5 average rating, 117 reviews

SALE OffGrid DOMEglamp*LEAFpeep*Adventurers Only

EXPERIENCE The Dome in the Woods • IMMERSE in complete silence with the absence of electricity: no hum or vibrations from this completely solar/propane fueled geodesic dome. NoAC • GLAMP in this OFF GRID ADVENTURE. 430 sq ft floor plan. 14 ft ceiling. 20 ft bay window with endless nature view at the foot of your bed. Lofted 7ft. • STARGAZE from the deck or fire pit • NESTLE in the romantic wooded nature of southeast MO. S of St Louis.N of Memphis • UNPLUG, UNWIND, RELAX. Adventure seekers only!

Guest favorite

Cabin in Perryville

5 out of 5 average rating, 43 reviews

Escape At Eagle View

This 1946 "caretakers" cabin sits high on a hill over looking the spectacular views of the Mississippi basin farmland. Our cozy one bedroom with loft cabin has much to offer in a private setting. The kids will enjoy the ladder stairs to their own special indoor camping/sleeping area. The kitchen is fully equipped for preparing meals or enjoy the outdoor kitchen on the large patio with a Green Egg or Weber gas grill, and built in stone fire pit. Wood fire pizza oven for additional fee.

Guest favorite

Guest suite in Perryville

4.96 out of 5 average rating, 341 reviews

Tranquil Retreat! Serene, Spacious Guest Suite!

This Private Guest Suite is nestled on the lower level of the home and offers a peaceful, private setting with great charm in which to rest and relax during your travels. ✦Features....... ✦ Just 4 min from I-55 ✦ Queen-size bed with Memory Foam topper ✦ Sofa bed with memory foam mattress ✦Quiet peaceful a ✦ 55" Roku TV w/ surround sound ✦55" TV in Master bedroom with Roku ✦Located at the end of a private lane - NO through traffic ✦NO Steps! ✦Home Gym ✦Parking right outside of entrance

Guest favorite

Treehouse in Perryville

4.95 out of 5 average rating, 110 reviews

Rustic reTREEt Treehouse Getaway

This treehouse features a gorgeous floor-to-ceiling stone indoor/outdoor fireplace, vaulted ceiling, and many large windows which provide natural light and beautiful views. The interior design fuses natural elements of wood and stone, with a more refined and polished urban country look. A partition wall creates intimate spaces w/in this large (950 sq.ft.) open floor plan. Highlights: king size bed, corner claw tub, rainfall shower, reading area, 65" TV, large deck, & BBQ grill.

Guest favorite

Treehouse in Perryville

5 out of 5 average rating, 582 reviews

TreeLoft at BaseCamp

Welcome to the TreeLoft experience! This is a custom built luxury treehouse for two. It is our hope that upon your stay you will be reconnected to nature and to the one you came with. We created the TreeLoft with an inspired state of mind, and we are hopeful that same inspiration will be experienced and reflected during your stay. Go to sleep counting stars and wake up with the trees! We can't wait to provide you with the TreeLoft experience! We rise by lifting others!

Guest favorite

Cottage in Ava

4.94 out of 5 average rating, 98 reviews

Crazy Joe's Cabin #1

We have 3 great rentals. Crazy Joe’s Cabin # 2 and Hickey House on Airbnb. Located 2 miles off rt. 151 in Shawnee National forest. The cabin is along tree line just west of Crazy Joe’s Fish House. Restaurant is open at 4pm Wednesday, Friday and Saturday 1bedroom cabin with queen bed, living room with queen sleeper sofa. Full kitchen, bathroom with shower,washer/dryer. Great place for hunting or fishing trip or get away. Smart tvs you can access apps

Guest favorite

Farm stay in Perryville

4.98 out of 5 average rating, 64 reviews

Kirn's Hummingbird Haven

Relax and enjoy the quiet country life at its best. Observe wildlife, enjoy the birds, watch the sunrise at our unique getaway. Nearby places of interest: Missouri National Veterans Memorial, National Shrine of our Lady of the Miraculous Medal, St. Mary's of the Barrens, American Tractor Museum, Perry County Community Lake--Missouri Department of Conservation all within 10 minutes. Lutheran Heritage Center and Museum in Altenburg MO (25 miles).

Superhost

Home in Altenburg

4.86 out of 5 average rating, 29 reviews

Historic House in the heart of Altenburg

Stay in this historic 1911 house ("The Inn") in the heart of Altenburg. Walking distance to the Lutheran Heritage Center and Museum, The Bank Coffee Shop, and the Saxony Hills Brewery, this house is centrally located. Recently remodeled kitchen and bathrooms provide updated amenities along with five spacious bedrooms and living areas. This is a great home for family reunions, events, and spending peaceful nights in the country.

Guest favorite

Home in Perryville

5 out of 5 average rating, 15 reviews

German-Inspired Home in Perryville

Welcome to our cozy Perryville retreat, where American charm meets German hospitality. Nestled in the heart of Perryville, Missouri, this fully renovated house is the perfect place for work or leisure. Immerse yourself in the harmonious blend of American comfort and European flair, and let this house become your home away from home.