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Vacation rentals in Pike County

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Top-rated vacation rentals in Pike County

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Rental unit in Hannibal

4.86 out of 5 average rating, 14 reviews

Brew View Loft

Welcome to BrewView Loft, a cozy private studio, in the heart of historic downtown Hannibal. Nestled above Great River Brewing Co, this charming Airbnb offers great views of the mighty Mississippi. Enjoy the perfect blend of comfort & ease with access to local attractions, shops, & restaurants. Whether you're here for a romantic getaway or a weekend of exploration, BrewView provides the ideal setting for a memorable stay. Relax on the balcony w/ a local brew! The perfect Hannibal retreat awaits!

Guest suite in Hannibal

4.92 out of 5 average rating, 25 reviews

Becky’s Suite - Friendship Brewery

Welcome to your perfect getaway above Friendship Brewery and Sidekick BBQ in Hannibal, Missouri! This cozy guest suite offers a unique blend of comfort and excitement. Enjoy access to our charming brewery and mouthwatering barbecue just steps away. After a day of exploring Hannibal's historic sites, unwind in your private retreat, complete with all the amenities you need for a memorable stay. With craft beer, delicious barbecue, and local charm at your doorstep, your Hannibal adventure awaits!

Home in Hannibal

4.96 out of 5 average rating, 91 reviews

Little House in the Hollow

Enjoy a private peaceful setting that is Conveniently located. Large fenced in yard for the kids and/or pets. Also has a 4 person hotub which is available year-round. The house is fully stocked for convenience. The house also has covered parking, outdoor fire pit, BBQ grill a play place for the kids and more. You will be within walking distance of 2 National Landmarks (Mark Twain Cave, Cameron Cave) as well as our Winery and Giftshop. Located just two miles from Hannibal's Historic District.

Home in Pittsfield

4.84 out of 5 average rating, 221 reviews

Florence Guest House

This 1,200 sq. ft. PRIVATE BOOK is a 174 year old building that Abe Lincoln stayed in. Central A/C, Forced air heat, Two decks (one overlooking the Illinois River), burn pit, outside grill, fully equipped kitchen, screened in porch, ample parking, access to the Illinois River/ boat ramp near, tie up on Our Private Lots! NOTE: RECENTLY HAD Guests' wanting to "JUST GET AWAY" for A Time!!! WE'RE HERE, IF YOU NEED YOUR PRIVATE TIME ALONE, AS WELL!!! ***NEW KEURIG; BRING YOUR K-CUPS!!!***

Home in Bowling Green

4.97 out of 5 average rating, 205 reviews

Peaceful Country Cottage

Traveling for work or pleasure? Enjoy a peaceful country view while relaxing on the front porch. This home sits on 14 acres, just off US Highway 61. Guests will see deer roaming in the yard early morning and at night. This rental accommodates families traveling with children or the couple seeking a quiet retreat. Stay here while you visit family and friends in the area. It is a short drive to Vandalia, Louisiana, Hannibal or Mark Twain Lake. (40 Min). About one hour from St. Louis.

Guesthouse in Pittsfield

4.85 out of 5 average rating, 20 reviews

Private Guesthouse Kitchen Washer Dryer Dishwasher

Hunting or visiting Pike county near Pittsfield, Illinois. We have the perfect place for you. Sleeps 5. Twin over Full bunk bed with trundle sleeps 3. 2 Futons couches that turn into 2 beds. Has what you need and more. Has a Stove, refrigerator, microwave, dishwasher, laundry washer and dryer. That's right get your laundry done before going home! Walking distance to town square Coffee shops, stores, restaurants, ice cream This also has a flat screen TV to watch live tv! Free WiFi!

Home in Griggsville

4.89 out of 5 average rating, 85 reviews

Arrowhead Farmhouse, Spacious home, scenic views

Newly renovated in the modern farmhouse style, this 2000+ square ft. ranch home will accommodate multiple families or groups. Conveniently located along I-72 in between Pittsfield & Griggsville, Illinois; Arrowhead Farmhouse sits in farming country. It has all the comforts of home and offers privacy in a scenic setting. We offer keycode access for check-in and check-out, but live close to property and are available if you have any questions or need assistance during your stay.

Home in Hannibal

4.99 out of 5 average rating, 178 reviews

Night at the Twain Museum

Night at the Twain Museum gives travelers an immersion experience into the life of Mark Twain, with a carefully curated collection charmingly presented. Experience a masterpiece museum in a relaxing atmosphere for an extended time. Warm and inviting home with perfect hospitality. Luxury Sleep Number King bed with 65” smart TV. Comfy Casper King is the second bed. Blackout bedroom blinds. Newly remodeled home. New sofa sectional with 65" smart TV. Front & back decks. Close to Main St.

Rental unit in Hannibal

5 out of 5 average rating, 11 reviews

Center St Suite

After an all new renovation this unit boasts a private entrance into an open concept living room and kitchen. Just off the massive fully equipped kitchen is the main bathroom with an all tile shower boasting a speaker in the ceiling and unlimited hot water. You'll be cosy in the master bedroom on the king bed undernieth the vast mountain mural. The second bedroom equipped with a futon for sleeping has its own half bathroom and a full size laundry making longer stays a breeze.

Home in Pittsfield

4.93 out of 5 average rating, 15 reviews

The Cozy Ranch

Charming, unique 3-bed, 1-bath home🏡 Located centrally in a quiet neighborhood within walking distance to many attractions in Pittsfield, Illinois. 5 minute drive to Yogi Bear’s Jellystone Park. Hunters Welcome; we cannot wait to host you! Spacious living area, modern kitchen, and a large backyard including a patio with a fire pit, 🔥and a basketball court. 🏀 Enjoy your morning coffee or an evening cocktail 🍹 out on the patio!

Home in Louisiana

4.93 out of 5 average rating, 29 reviews

The Yellow Rose Historic Home

This cozy home is 8 blocks to the Mississippi. Beautiful overlooks, nice restaurants, historic homes. A short drive to Two Rivers Marina, the SLU Lay Center Sculpture Park, Hopewell Winery, Ted Shanks Conservation Area, Clarksville Apple Shed. 30 min. to Hannibal, MO - home of Mark Twain. 45 min. to Mark Twain Lake. 90 min. to St Louis. Plenty of sight-seeing, hunting, fishing, boating in the area. Fur babies are welcome.

Rental unit in Hannibal

4.85 out of 5 average rating, 143 reviews

Farmhouse

Enjoy nostalgic downtown Hannibal in this unique apartment located on Main Street just steps from a movie theater, restaurants and bars, shopping, museums, the riverfront, and Mark Twain historic sites. With a private bedroom with flat screen television, living area with sleeper sofa and daybed, and a full kitchen the interior of this rental is sure to charm any visitor. Book for a weekend, a week, or longer.

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Popular amenities for Pike County vacation rentals

Free parking on premises

Air conditioning

Other great vacation rentals in Pike County

Hotel room in Hannibal

4.9 out of 5 average rating, 110 reviews

Honeymoon Suite 2

Rental unit in Hannibal

5 out of 5 average rating, 8 reviews

Molly Brown: Two-level/1BR/1Bath

Private room in Pittsfield

4.86 out of 5 average rating, 35 reviews

Sloth Lodging (Upper Level)

Home in Quincy

4.86 out of 5 average rating, 7 reviews

Cottage with Open Floor Plan

Private room in Hannibal

5 out of 5 average rating, 25 reviews

Cinnamon Room at The Quarry House

Hotel room in Louisiana

5 out of 5 average rating, 8 reviews

The Eagles Nest Inn

Home in Hannibal

4.95 out of 5 average rating, 21 reviews

The Eleanor Davis House with POOL

Private room in Hannibal

4.97 out of 5 average rating, 29 reviews

Charming Suite 3 blocks from Main St.

Destinations to explore