Guesthouse vacation rentals in Pima County

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Pima County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Tucson

4.95 out of 5 average rating, 826 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (1-19-2024) "59 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the Eucalyptus Suite Airbnb and the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 170 reviews

Charming Private Oasis Casita with Pool & Hot Tub

Here at the Double H Hacienda you will find a cozy and charming detached guest house with private entrances, plenty of parking (covered available). Plenty of natural light and a design that is all its own - where modern farmhouse meets the desert. It comes stocked with all the amenities you could desire including in-unit laundry and kitchen. Beautiful 360 degree views of the mountains and Tucson's breathtaking sunsets from anywhere on the property. Equine Experiences available for all guests!

Guest favorite

Guesthouse in Tucson

5 out of 5 average rating, 258 reviews

Cottage

Casita Rosada is a converted artist's studio in the Tucson Mountain foothills surrounded by native desert vegetation yet only 15 minutes from downtown. A bright, spacious interior decorated in the Southwest tradition, twelve foot ceilings, comfy chairs, and a pillow-top queen bed make it your ideal home away from home. Have coffee on the porch and watch the sunrise, observe wildlife, gaze at the mountains, and view the city lights each night. Hiking trails and bike paths are both within a mile.

Guest favorite

Guesthouse in Tucson

4.94 out of 5 average rating, 155 reviews

Private Casita in Casas Adobes

411sq ft private Casita just newly REMODELED! Sleeps up to 4. King feather bed & a pullout sleeper. Located just past a quaint garden where you can catch hummingbirds drinking. Private parking & entrance, just come and go. ASK ABOUT: Our other King Suite just feet away! Can sleep 2 more! ROMANTIC PKG add on for $69 Cool off in pool (rarely used by us), use outside patio (where cooking station is located, there's no kitchen in the casita). Min. from I-10 & stellar Tucson Biking Loop!!

Guest favorite

Guesthouse in Tucson

4.97 out of 5 average rating, 749 reviews

Private Tucson Desert Guest House Getaway

This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 184 reviews

Cozy Mountain Retreat w/ Hot Tub

Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 302 reviews

Time Capsule in the Sonoran Desert

Time Capsule is a unique experience in an space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design we cannot accept any pet, service animal, nor children in the Time Capsule. Please note that check in is in person only and not later than 10:00PM. No exception!

Guest favorite

Guesthouse in Tucson

4.99 out of 5 average rating, 101 reviews

Charming Private Guesthouse with Mountain View

Enjoy the beautiful mountain view from the cozy wrap around porch. Perfect for your morning coffee. Private guest house located on small horse ranch. Close to hiking, biking, and site seeing. Cozy up to the fire pit in the evening to watch the eastern mountains turn pink as the sun sets in the west. Check out our 100 plus 5 star reviews. This is truly a magical place. Non smoking of any kind, no pets, service animals, infants or children. Check out our weekly and monthly discounts!

Guest favorite

Guesthouse in Tucson

4.98 out of 5 average rating, 375 reviews

No Cleaning Fees!

Guest Quotes: "Coziness of an Airbnb & the amenities of a five-star hotel. Special touches are so welcoming! Sunrise and sunsets from the deck are spectacular! Perfect mix of City amentities & desert peace. Best Airbnb experience ever. Love the wildlife. Like your own personal botanical garden. Host was attentive but not intrusive. We felt right at home. Charming, Magical, Spacious, Peaceful, Comfortable, Beautiful, Amazing. Extremely Clean. A sanctuary in uncertain times."

Guest favorite

Guesthouse in Ajo

4.99 out of 5 average rating, 186 reviews

Cozy hideaway cottage in historic Ajo

Stay in a cozy, very private, window filled 500 sq. ft. hideaway cottage that is located on the property of a historic Ajo home. Located just 4 blocks from the gorgeous Spanish Revival town plaza, you can walk to Ajo's Visitors Center, art galleries, restaurants, library, and coffee shop or you can drive a mile to the Ajo Scenic Loop to savor and hike a portion of the pristine Sonoran Desert that rivals Organ Pipe Cactus National Monument. Let me welcome you to Ajo!

Guest favorite

Guesthouse in Tucson

4.96 out of 5 average rating, 281 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in the Sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge in the sun or shade on the deck or under louvered patios. Close to the UA and downtown. Book now and escape the ordinary!

Guest favorite

Guesthouse in Rio Rico

4.87 out of 5 average rating, 336 reviews

Cozy Rio Rico guesthouse with a view

This spacious guesthouse is in an ideal rural setting. Located near the Mexican border, the art community at Tubac, and the old Spanish mission of Tumacacori, there is lots to see and do. (Not to mention many good golf courses.) I am looking forward to your visit! To make your stay both pleasant and sanitary I steam clean floors, sani-wash all linens and towels, and wipe counters, sinks and toilet with sanitizer spray. Rest easy here!