Hotel vacation rentals in Santa Cruz Department

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Santa Cruz Department

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Superhost

Hotel room in Santa Cruz de la Sierra

4.75 out of 5 average rating, 67 reviews

Luxurious 5 Star Hotel Suite in Equipetrol area

Located in the best neighborhood in the city, Barrio Equipetrol. You'll be staying in a 118m2 Suite at a 5-Star hotel where you can enjoy the safety and comfort of a top-rated hotel. Work trip? With a co-work space and blocks away from the Business Area of the city. Coming to explore Santa Cruz? Only steps away of San Martin Avenue to visit the most trendy restaurants, shopping malls and social experiences in Santa Cruz. Also located only 10 minutes away from the historical center of the city

Superhost

Hotel room in Santa Cruz de la Sierra

4.8 out of 5 average rating, 5 reviews

Comfortable, Central and Cultural Estancia!

Missionary provides a comfortable, clean, and safe environment. The room has air conditioning and a private bathroom. There is a 24-hour front desk and free WiFi throughout the facilities. Each environment is equipped with table desk, flat screen TV and dryer, hot shower. A buffet breakfast is served every morning. Missional is close to the metropolitan cathedral, September 24 metropolitan square, restaurants, banks, shops and markets to enjoy your visit to the city.

Guest favorite

Private room in Valle Sánchez

4.87 out of 5 average rating, 53 reviews

A few minutes from the airport.

After a tiring trip, nothing better than resting in a peaceful and peaceful place while waiting for your next destination. If you are an animal and plant lover you will feel especially loved and accompanied by nature and our pets if you wish. In the swing of the hammock you can read a good book, listen to music or enjoy a delicious grilled meat with vegetables and have some delicious juices with fruits of the season.

Superhost

Casa particular in Santa Cruz de la Sierra

4.8 out of 5 average rating, 20 reviews

Very comfortable house 3 rooms

Very comfortable house with three spacious bedrooms and 2 full baths, kitchenette, dining room, shared pools, shared pools, shared churrasqueras, green trails, large gardens, Polo courts, tennis, soccer and basketball and a beautiful natural lagoon. has free parking, WiFi, TV. Located 20 minutes from downtown very close to Viru Viru Airport