Boutique hotel vacation rentals in South Italy

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in South Italy

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Superhost

Hotel room in Roma

4.87 out of 5 average rating, 181 reviews

Relais Santa Caterina - The Suite

Il Relais Santa Caterina della Rosa sorge all'interno di un palazzetto del 16 secolo, ex convento e sede storica del Conservatorio di Santa Caterina. La Suite Superior è una location unica, 90 mq, totalmente affrescata, le sue finestre affacciano direttamente nella navata della chiesa sottostante. Dotata di wi-fi, smart tv, frigo bar e cantina dei vini, climatizzata è la soluzione ideale per famiglie o piccoli gruppi che scelgono un posto unico, in pieno centro storico per il loro soggiorno.

Guest favorite

Hotel room in Sorrento

4.97 out of 5 average rating, 174 reviews

Sorrento-Mansarda Old Town without window

By staying at Palazzo Delle Grazie you will experience the magical atmosphere rich in history that only the historic center of Sorrento can offer you. The historic building that houses the facility has been entirely restored, used and designed to offer its guests all the comforts necessary for a pleasant stay. A rich continental breakfast is included in the reservation. Tourist tax of €4.00 per day per person not included in the price (from 1 April to 31 October) CODICE CUSR 15063080EXT0742

Superhost

Hotel room in Roma

4.84 out of 5 average rating, 271 reviews

Del Falco - San Pietro Boutique Rooms

Del Falco -St. Peter's Boutique Rooms is located in the heart of Rome, and housed in a 17-century building. It's 1 minute walking from St Peter's Basilica and 300 metres from The Vatican Museum, Castel Sant'Angelo and Metro station. Every room has a contemporary style and vintage details. Each is fitted with a flat-screen TV and A/C. Rooms are equipped with private bathroom, bidet, shower or jacuzzi, free toiletries and a hairdryer. There's a lounge area. Free WI-FI.

Superhost

Hotel room in Roma

4.78 out of 5 average rating, 109 reviews

Palazzo del Duca Piazza Navona Roma Suite

In its 50 square meters, finely finished, this wonderful Suite with an antique flavor in the heart of Rome, is the ideal place to experience the city in total comfort. Available for guests: private living room with kitchenette; bathroom with separate shower and tub; air conditioning and heating, safe, mini fridge, hairdryer, wi-fi internet connections, smart TV; Netflix and kettle kit. Thanks to a comfortable sofa bed it can accommodate up to 4 people.

Guest favorite

Hotel room in Fiumefreddo Bruzio

4.95 out of 5 average rating, 97 reviews

The hospitable style of a seaside village in Calabria

The period residence offers numerous common areas: reading rooms, kitchen, breakfast room and terrace. The rooms are equipped with Wi-Fi, numerous balconies and windows overlooking the Tyrrhenian Sea. The beach is only 3 km from the ancient village. The "Vico Granatello" Residence offers the typical lifestyle of a village, made of tranquility, conviviality, good and authentic things. Our motto is: "the beautiful, the good and the healthy".

Guest favorite

Hotel room in Matera

4.89 out of 5 average rating, 210 reviews

Vicolo Fiore Affittacamere - CAVEOSO Room

Vicolo flower rentals, is in a strategic position to visit the Sassi di Matera and at the same time be able to park freely along the streets. Located inside the Historic Center, it will be the ideal structure for you. We have 4 rooms but this listing is about the CAVEOSO Room, a Standard Double with terrace * BREAKFAST (served at affiliated bar) * PARKING (free on the street) * FRONT DESK (11am or Self check-in) * LUGGAGE DROP-OFF (free)

Superhost

Hotel room in Roma

4.82 out of 5 average rating, 2,354 reviews

38 Viminale Hill - Double Room 2

Our Guest House will allow you to visit the wonders of Rome on foot! Near Termini station, in front of the Opera House is the ideal location to spend a vacation in the Eternal City. Ultra-fast internet connection, emotional shower, chromotherapy, wet bar, 24 hours a day. The Colosseum, Trevi Fountain and Spanish Steps are a 15-minute walk away, and the Vatican is a 10-minute subway ride away. We look forward to seeing you!

Guest favorite

Hotel room in Pompei

4.95 out of 5 average rating, 261 reviews

Pompei Plaza - Junior Suite *Sanctuary View* #102

Situato vicinissimo alla piazza principale e a pochi passi dalle rovine antiche di Pompei, Pompei Plaza si trova nel cuore della città, a solo due minuti a piedi dalla stazione Pompei Santuario. Pompei Plaza offre una camera climatizzata con Wi-Fi gratuito, Smart TV 50 pollici e macchina del caffè Nespresso. A vostra disposizione troverete anche un parcheggio custodito con una tariffa di 15€ al giorno.

Guest favorite

Hotel room in Dubrovnik

4.91 out of 5 average rating, 65 reviews

Old Town B&B 2

Our town house is situated in the heart of Dubrovnik's historic Old Town, strategically positioned for easy access with minimal steps to navigate. Unlike other areas of the town, which require climbing numerous steps, our location is conveniently close to the main street, ensuring a hassle-free arrival. Enjoy the charm and heritage of a home that has been cherished by our family for years.

Guest favorite

Hotel room in Positano

4.93 out of 5 average rating, 257 reviews

Casa Guadagno - Positano Amalfi Coast

In this listing there are photos of multiple rooms, one of which will be assigned to you, based on availability at the property. Casa Guadagno is a family business founded in 1957 by Antonio Guadagno. Today as back then, guests can feel at home, in a pleasant and familiar environment, to spend a relaxing holiday in a setting that only a few places in the world can offer.

Guest favorite

Hotel room in Positano

4.9 out of 5 average rating, 118 reviews

Charming Double Room in Fornillo

Double lovely room equipped with all comforts and part of the Hotel Dimora Fornillo. The room is overlooking the bay of Fornillo from its charming balcony. In your bright room you will find: Tv, safe, wardrobe, desk, minibar,a/c, private bathroom with toiletries, and wifi. Beach towels are available on request. Great breakfast is offered every morning!!

Guest favorite

Hotel room in Lecce

4.74 out of 5 average rating, 188 reviews

Palazzo Caminanti room3

Antica dimora situata in una tranquilla zona del centro storico leccese. Ottima per chi vuole conoscere e visitare la città e come punto di partenza per esplorare la penisola salentina. Camera matrimoniale o tripla su richiesta . Caminanti nasce dall 'idea di due amici di costruire un luogo preposto a un'accoglienza familiare.