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Guesthouse vacation rentals in Southern Indiana
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Southern Indiana
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Southern Indiana guesthouse rentals
Family-friendly guest house rentals
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Guesthouse in Brownsburg
4.86 out of 5 average rating, 502 reviewsCozy Guest House in the Big Woods
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Guesthouse in Evansville
4.89 out of 5 average rating, 565 reviewsNest: 1905 Carriage House Apartment
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Guesthouse in French Lick
4.94 out of 5 average rating, 196 reviewsThe Guest Suite at Château Carson
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Guesthouse in Frankfort
4.99 out of 5 average rating, 100 reviewsTreetop Hideaway
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Guesthouse in Harrisburg
4.97 out of 5 average rating, 298 reviewsNew! Enjoy the Hot Tub under Pagoda #SNForrest
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Guesthouse in Louisville
4.99 out of 5 average rating, 373 reviewsHighlands - Elegant Calm Clean & Green - Walkable
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Guesthouse in Louisville
4.93 out of 5 average rating, 289 reviewsCharming Carriage House with 2 private baths.
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Guesthouse in Louisville
4.98 out of 5 average rating, 253 reviewsHighlands Carriage House
Guest house rentals with a patio
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Guesthouse in Louisville
5 out of 5 average rating, 171 reviews*BRAND NEW* Gem of Germantown Private Derby Suite
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Guesthouse in Maineville
4.96 out of 5 average rating, 166 reviewsThe Barn at Serenity Acre
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Guesthouse in Hamilton
4.99 out of 5 average rating, 155 reviewsPeaceful Little Cabin Retreat - escape in nature
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Guesthouse in Lexington
4.96 out of 5 average rating, 114 reviewsCozy studio with private pool and firepit
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Guesthouse in Louisville
4.98 out of 5 average rating, 105 reviewsCharming Carriage House in Old Louisville
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Guesthouse in Dubois
4.78 out of 5 average rating, 63 reviewsRural Studio Guest-house Overlooking Corn Fields
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Guesthouse in Madison
4.94 out of 5 average rating, 62 reviewsStudio apartment above Garage in downtown Madison
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Guesthouse in Louisville
5 out of 5 average rating, 30 reviews2BR Sterling Springs Guest Suite
Guest house rentals with a washer and dryer
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Guesthouse in Bloomington
4.99 out of 5 average rating, 192 reviewsCozy and Convenient
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Guesthouse in Louisville
4.97 out of 5 average rating, 117 reviewsThe City Cottage…quiet, peaceful, and convenient!
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Guesthouse in Indianapolis
4.99 out of 5 average rating, 807 reviewsPrivate and Charming Carriage House Downtown Indy
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Guesthouse in Indianapolis
4.96 out of 5 average rating, 281 reviewsHidden Orchard Guest Cottage
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Guesthouse in Cincinnati
5 out of 5 average rating, 190 reviewsPerch Farm's Guesthouse with Incredible View
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Guesthouse in Indianapolis
4.99 out of 5 average rating, 303 reviewsLuxurious Guest House Central to Everything
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Guesthouse in Jeffersonville
4.88 out of 5 average rating, 186 reviewsThe Cottage Next Door
Guesthouse in Loveland
4.98 out of 5 average rating, 500 reviewsRetreat to a Boho Chic Guesthouse in a Leafy Family Suburb
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