Vacation rentals in St. Charles County
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Top-rated vacation rentals in St. Charles County
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
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Popular amenities for St. Charles County vacation rentals
Other great vacation rentals in St. Charles County
Guest favorite
Condo in Saint Charles
4.94 out of 5 average rating, 142 reviewsCozy Studio in Beautiful New Town St. Charles
Jan 14 – 21
$137 per night
Guest favorite
Loft in Alton
4.94 out of 5 average rating, 151 reviewsFantastic River View - Upscale 2BR/2BA Loft w/deck
Apr 28 – May 5
$126 per night
Guest favorite
Home in Kirkwood
4.98 out of 5 average rating, 175 reviewsA Kirkwood Cottage, Quaint Suburb of St Louis
Aug 31 – Sep 7
$138 per night
Guest favorite
Home in Saint Charles
5.0 out of 5 average rating, 225 reviewsRustic Handcrafted Japanese-Style Home by OldTown
Feb 1 – 8
$174 per night
Guest favorite
Guest suite in Dardenne Prairie
4.89 out of 5 average rating, 197 reviewsTreehouse Spa Suite
Sep 24 – Oct 1
$68 per night
Guest favorite
Loft in Saint Charles
4.81 out of 5 average rating, 43 reviewsCity Loft in Saint Charles
Aug 13 – 20
$95 per night
Guest favorite
Home in Saint Charles
5.0 out of 5 average rating, 22 reviewsLittle House By Main St -5 4K TV's- 1-75 Inch -1GB
Nov 25 – Dec 2
$136 per night
Guest favorite
Home in Saint Charles
4.88 out of 5 average rating, 57 reviewsThe robin nest a cozy cottage on historic main str
Mar 5 – 12
$102 per night
Destinations to explore
- Rentals with a fireplace St. Charles County
- Private suite rentals St. Charles County
- Condo rentals St. Charles County
- Monthly Rentals St. Charles County
- Rentals with a patio St. Charles County
- Rentals with pools St. Charles County
- Rentals with breakfast St. Charles County
- Hotel rentals St. Charles County
- Rentals with an accessible height toilet St. Charles County
- Rentals with lake access St. Charles County
- Fitness-friendly rentals St. Charles County
- Rentals with an EV charger St. Charles County
- Loft rentals St. Charles County
- Rentals with a washer and dryer St. Charles County
- Pet-friendly rentals St. Charles County
- Kid-friendly rentals St. Charles County
- Rentals with a fire pit St. Charles County
- Apartment rentals St. Charles County
- Rentals with a hot tub St. Charles County
- House rentals St. Charles County
- Smoking-friendly rentals St. Charles County
- Rentals with outdoor seating St. Charles County
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