Hotel vacation rentals in Tisbury

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Top-rated hotel rentals in Tisbury

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Hotel room in Woods Hole

4.65 out of 5 average rating, 107 reviews

Treehouse Lodge, Canopy style rooms

This beautiful modern meets classic style property is a 10-minute walk from the beach and ferry to Martha's Vineyard in Woods Hole. Free private parking and free WiFi is available on site. Quick walk to the beach, several restaurants, and most science facilities. Guests can enjoy various activities in the area, including windsurfing, fishing and traveling to Martha's Vineyard. *Note to bookers- We are located on the mainland where you get the ferry to go to Martha's Vineyard*

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Private room in West Yarmouth

5 out of 5 average rating, 6 reviews

August 8-15.Riverview Resort! Two baths. 6 people

August 8-15, 2025. Sleeps six. Master bedroom: King-size bedroom ensuite and sofa bed; THEN, in living room, another sleeper sofa and half bath. Large refrigerator/freezer. Free parking, 2TVs, cable, wifi, AC. First level with sliding doors to beautiful courtyard overlooking Parker River with BBQ grills. On-site washer/dryer, kitchen,exercise,game room. Near beaches. Across from Captain Parker’s Restaurant and Pirates Cove putt-putt. Indoor pool; hot tub;gym. $2,000 week!

Hotel room in Sandwich

4.57 out of 5 average rating, 550 reviews

Boutique 1950s Cape Cod motel

We are a small 1950s motel in a tranquil setting. You drive up to your room. We offer breakfast, housekeeping, and have guest laundry and vending and ice. Every room has a frig, microwave, coffee and tea service, and bath amenities. We offer suites with kitchenettes but these you book directly with us. You have to be 21 to rent a room, we are no pet-friendly, and 100% non-smoking. There are places to smoke. Office is open 6am-10pm. You can check-in after, just let us know.

Guest favorite

Hotel room in Tisbury

5 out of 5 average rating, 48 reviews

2 Bedroom Luxurious Suite -Kitchen & Living Room

Charles & Charles B&B close to restaurants and dining, the beach, and nightlife. Our AQUINAH SUITE is on the second floor and has a lovely living room and a fully equipped eat in kitchen. We have 100% cotton linens in all our rooms along with complimentary use of our bicycles, beach chairs and beach towels. We serve a cooked breakfast served at poolside everyday. We only allow children 12 years of age and older. For special weekly winter rates, please contact us.

Superhost

Hotel room in Edgartown

4.8 out of 5 average rating, 64 reviews

THE FRANKLIN HOTEL~NEW Pet friendly Standard Queen

Located on Upper Main Street in Edgartown, the Franklin Hotel is a short stroll from the heart of the historic village and its famed island beaches. A fresh take on the nautical style with modern, luxury finishes will provide all you need for work, play and relaxation. The Franklin grounds offer distinct seating areas including the covered patio, perfect to enjoy three season island breezes. The chic design of our 18 guestrooms will delight every sense.

Guest favorite

Hotel room in Oak Bluffs

4.96 out of 5 average rating, 71 reviews

In Town Queen Room

The Attleboro House has all of the conveniences of a modern hotel in the quaint atmosphere of a historic inn. Located among the famous Gingerbread Cottages and directly on the Oak Bluffs harbor, you’ll be in the perfect place for your visit to Martha’s Vineyard. Originally built in 1874, The Attleboro House was completely renovated in 2018. Relax on our wrap around porch to enjoy the bustling harbor and impressive views of the Nantucket Sound.

Guest favorite

Hotel room in Falmouth

4.91 out of 5 average rating, 58 reviews

Park Side Queen Room @ Frederick William House

This beautifully appointed room with private bath & sitting area, includes bike rentals, cable, free WIFI, overlooking gardens & park. We are located on the Shining Sea Bikeway in Falmouth, across the street from Goodwill Park, a short walk to the Steamship Authority. Guest are welcome to take bikes over to Martha's Vineyard for day excursions. Beach passes are available, 139 private & public beaches to choose from.

Hotel room in Tisbury

4.74 out of 5 average rating, 84 reviews

Vineyard Harbor - Harbor View Unit 237

Vineyard Harbor offers comfortable rooms, a private beach and an incredible location. We are situated on the harbor in Vineyard Haven within walking distance to the ferry, unique shops, great restaurants and perfectly placed to explore the island. Vineyard Harbor is the perfect location from which to explore Martha’s Vineyard.

Guest favorite

Hotel room in Hyannis Port

4.84 out of 5 average rating, 97 reviews

#8 Queen private bath. No daily maid service

Private rooms, private bath, wifi, continental breakfast daily at Salt Winds. Walk to beach and town and enjoy all Hyannis has to offer. Island ferry one mile to both Islands, 1 hour drive to PTOWN. Parking, pool no glass in pool area, beach towels and chairs available. Other rooms available sorry no pets allowed

Vacation rentals for every style

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Popular amenities for Tisbury hotel rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly hotel rentals

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Hotel room in Falmouth

4.87 out of 5 average rating, 45 reviews

Luxury SeaSide King Suite, Frederick William House

Hotel room in East Dennis

5 out of 5 average rating, 4 reviews

Deluxe Efficiency Room at the Sesuit Harbor House

Hotel room in East Dennis

4.85 out of 5 average rating, 13 reviews

Deluxe Queen Room at Sesuit Harbor House

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Hotel room in Falmouth

4.86 out of 5 average rating, 21 reviews

Harborside G King Suite @ Frederick William House

Hotel room in Teaticket

4.62 out of 5 average rating, 60 reviews

Courtyard Room

Guest favorite

Hotel room in Falmouth

4.95 out of 5 average rating, 21 reviews

Deluxe Black King Suite @ Frederick William House

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Hotel room in Yarmouth

4.34 out of 5 average rating, 73 reviews

Ultimate Vacation Home, NoSmoking Room with 2 Beds

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Hotel room in Falmouth

4.9 out of 5 average rating, 58 reviews

Glendale Petite @ Frederick William House

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Hotel rentals with a pool

Hotel room in Falmouth

4.29 out of 5 average rating, 70 reviews

Guest Room with 1 King Bed

Hotel room in Hyannis

4.23 out of 5 average rating, 146 reviews

Regency Suite

Hotel room in West Barnstable

4.72 out of 5 average rating, 29 reviews

Private, converted 1740 horse stable at inn. Kitchen, and lots of space!