Guesthouse vacation rentals in Lexington County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Lexington County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Lexington County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Columbia
4.87 out of 5 average rating, 90 reviewsCozy Camper in St. Andrews, Irmo, Harbison Blvd.
Guesthouse in West Columbia
4.95 out of 5 average rating, 649 reviewsCarriage House: Studio Bed & Bath - Pool & Hot Tub
Guesthouse in Lexington
4.94 out of 5 average rating, 261 reviewsCome Pause and Relax!
Guesthouse in Columbia
5 out of 5 average rating, 400 reviewsCozy studio apartment, convenient location
Guesthouse in Columbia
3.98 out of 5 average rating, 43 reviewsClean, Affordable Cottage#3 near USC & Downtown
Guest house rentals with a patio
Guesthouse in Batesburg-Leesville
5 out of 5 average rating, 7 reviewsBeautiful Lake Front 1 bedroom Guest House
Guesthouse in Lexington County
4.97 out of 5 average rating, 35 reviewsMom's Place
Guesthouse in Lexington County
5 out of 5 average rating, 23 reviewsBoat House
Guesthouse in Columbia
4.85 out of 5 average rating, 103 reviewsCary Lake Guesthouse - Slice of Heaven
Guesthouse in West Columbia
4.93 out of 5 average rating, 15 reviewsAviation A-Frame Airbnb
Guesthouse in Chapin
New place to stayGuesthome Diamond of Lake Murray
Guesthouse in Columbia
4.74 out of 5 average rating, 47 reviewsThe Wren's Nest | 1BR 2BA Guesthouse
Guesthouse in Chapin
4.67 out of 5 average rating, 3 reviewsClover Cottage
Guest house rentals with a washer and dryer
Guesthouse in Columbia
4.93 out of 5 average rating, 96 reviewsBubba’s Tranquil Treehouse
Guesthouse in Columbia
4.94 out of 5 average rating, 36 reviewsCasa Abelia - Downtown Columbia
Guesthouse in Lexington
4.98 out of 5 average rating, 60 reviewsGuesthome
Guesthouse in Winnsboro
5 out of 5 average rating, 7 reviewsCountry bungalow - optional horse stable(s)
Guesthouse in Columbia
4.98 out of 5 average rating, 44 reviewsGraymont Place | Cottage near USC, Downtown, Vista
Guesthouse in Columbia
4.89 out of 5 average rating, 75 reviewsFaber's Rest LLC
Guesthouse in Lexington
5 out of 5 average rating, 12 reviewsGarage Apartment
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