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Vacation rentals in Mesa County

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Top-rated vacation rentals in Mesa County

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Farm stay in Glade Park

4.87 out of 5 average rating, 607 reviews

Darling Colorado Sweetheart Cabin!

Darling sweetheart cabin, located on a working horse ranch on top of the Colorado National Monument, 30 min from Grand Junction. This location is perfect for those seeking a unique place to stay while enjoying all the adventures available around the area including hiking trails, horseback riding, ATV riding, hunting, and some of the best mountain biking around. There is beautiful aspen covered,alpine high country nearby as well as red rock desert/ formations including a series of natural arches.

Home in Orchard City

4.95 out of 5 average rating, 460 reviews

The Orchard House

**A devastating freeze in October 2020 killed all 400 of our sweet cherry trees and many of our peach trees. Sadly, our orchard is not the lush green jewel it once was. We are planting new cherry trees in the Spring of 2022. While the orchard views have changed, the Orchard House continues to offer a very comfortable place to rest and recharge. Come enjoy fresh air and quiet whether you are stopping through on a road trip or staying longer for local adventure. Fast WiFi for telecommuting!

Tiny home in Palisade

5 out of 5 average rating, 285 reviews

Carriage House on Organic Peach Farm

Located on the Scenic Fruit & Wine Byway the Carriage House is on our organic three-acre peach farm within easy biking distance to downtown Palisade, surrounding wineries & hiking trails. Enjoy downtown Palisade's farmers market, distillery, brewery & restaurants. We're moments from many wineries & trailheads including access to The Plunge, Mt. Garfield, Palisade Rim & Riverbend Park. Begin, end or spend your day lounging in the little yard quaint for sipping wine & enjoying charcuterie.

Home in Loma

5 out of 5 average rating, 494 reviews

Fruita/Loma Guest House at the Perfect Day Getaway

This newly constructed "Green" home is a mix of modern and country styles and will surely inspire you to enjoy all of the outdoor activities the Grand Valley has to offer. The Perfect Day Getaway house is located on a quaint farm within 8 minutes of world-class hiking, mountain and road bicycling, and river rafting. It is a great launching point for day trips to Moab and the Grand Mesa as well! It was built to maximize the southern exposure and views of the Colorado National Monument.

Home in Palisade

4.96 out of 5 average rating, 248 reviews

Galloway Ranch Palisade Colorado

Recent review: The best place we've ever stayed at, hands down! The location felt like a dead end road, yet close to everything. The yard had beautiful flower beds, not to mention the amazing view of Mt. Garfield! The house itself was very comfortable and had anything you can imagine in the kitchen, making a few at home dinners a breeze. Owners Note: One (1) dog 45 lbs max allowed unless an additional dog is approved in advance, please include # of people and # of dogs when booking.

Home in Palisade

4.9 out of 5 average rating, 153 reviews

The Pali House B - Beautiful Home on 10 acres

Thank you for considering a stay at our newly remodeled home, designed with luxury and comfort in mind. Enjoy the privacy of being on 10 acres with incredible views while still being 3 minutes to wineries and 7 minutes to downtown Palisade. House B is the downstairs unit of this two story ranch home. With a private, walkout basement entrance, living room, dining room, and fully stocked kitchen. The large yard is recently landscaped and perfect for dogs! Your hosts, Joe & Trish

Guesthouse in Clifton

4.83 out of 5 average rating, 296 reviews

Colorado river guest house

Welcome to Happy Tails animal sanctuary we are a nonprofit animal rescue in palisade wine country. 10 acre animal sanctuary w alpaca, goats, pigs, dogs, chickens peacocks even a emu that all free range. Fish, kayak, paddleboard, canoe on our 2 acre fully stocked fishing lake. Float the Colorado river from Riverbend park in Palisade to our private beach. The views of the Colorado river, Grand Mesa & mount Garfield are breathtaking the animals are all friendly and love people

Farm stay in Fruita

4.99 out of 5 average rating, 217 reviews

Karie’s Hideaway Fruita *Quiet*Private*Secure*

Hideaway at this modern guest house north of Fruita. Visit the ostriches and horses. Perfectly located only 10 minutes from downtown Fruita and 20 minutes from Grand Junction. The home you'll stay in is in its own building. Starlink internet for fast and reliable Wi-Fi. The Hideaway offers safety and privacy, along with plenty of parking for vehicles, RV's and trailers. Relax on the covered front porch or play horseshoes, as you enjoy mountain views in every direction.

Place to stay in Mesa County

4.97 out of 5 average rating, 237 reviews

Thimble Rock Point

Nestled in the mountainside of an obscure Colorado canyon there is a place so fitting it literally rises from the rock the way a ship breaks a wave. Mimicking the geology and angular unconformity of the canyon walls, a harmonic relationship exists between roof pitch and steep granite cliffs. Built for the traveler who seeks more than shelter but an experience, the magic at Thimble Rock will evoke feelings of nostalgia, romance and the yearning to explore.

Tiny home in Hotchkiss

5 out of 5 average rating, 595 reviews

The Solargon

The Solargon is inspired by elements of Asian yurts, Navajo hogons and Native American hidatsa lodges. Combined with passive solar design principles, the solargon is an octagonal structure designed to take full advantage of the sun. The vaulted ceilings and plentiful windows make the solargon bright and inviting. This is a perfect spot for solo travelers or couples looking for a quiet, off the beaten path place to get away from it all.

Tiny home in Hotchkiss

4.95 out of 5 average rating, 373 reviews

Tiny House Farm Stay w/Kitchenette *Black Canyon*

This cute and cozy tiny house has easy access to the area's many attractions. Right on Hwy 92, 7 minutes to downtown Hotchkiss and 20 min to Paonia. 45 min to the Black Canyon's North Rim, 45 min to the Grand Mesa. World class fishing right down the road! High desert views of the Gunnison Gorge and the Uncompahgre Plateau. Well-stocked kitchenette. Fire pit! 100 Mbps WiFi. Dog allowed. No cats. Smoking OK outside, 420 friendly!

Cabin in Cedaredge

4.93 out of 5 average rating, 103 reviews

The Blue Bear Cabin - small home, big welcome!

The Blue Bear is a quiet, comfortable home base for your outdoor adventures and a peaceful place to reconnect with family and friends. Located a few miles outside of Cedaredge on the southern slope of the Grand Mesa, convenient to nordic and alpine skiing, hiking and fishing. Watch deer stroll through your amazing view of the Mesa during the day, and enjoy awesome stargazing around the firepit at night.

Vacation rentals for every style

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Popular amenities for Mesa County vacation rentals

Free parking on premises

Air conditioning

Other great vacation rentals in Mesa County

Home in Fruita

4.95 out of 5 average rating, 212 reviews

Maple Alley-Brand new in Downtown Fruita

Guest suite in Mesa

4.96 out of 5 average rating, 92 reviews

Cozy Log Cabin with views in Powderhorn Ski Resort

Home in Grand Junction

4.85 out of 5 average rating, 712 reviews

Happy Hippie House

Home in Paonia

4.92 out of 5 average rating, 676 reviews

Kale's Private & Romantic Cottage - King, Kitchen

Rental unit in Grand Junction

4.95 out of 5 average rating, 375 reviews

The Red Arches Airbnb

Home in Grand Junction

4.92 out of 5 average rating, 237 reviews

Colorful 2 bedroom pet friendly home

Guesthouse in Grand Junction

4.99 out of 5 average rating, 315 reviews

Chic 2 Bedroom Cottage with Monument Views

Guest suite in Loma

4.96 out of 5 average rating, 24 reviews

Loft with views very comfortable

Destinations to explore