We’re sorry, some parts of the Airbnb website don’t work properly without JavaScript enabled.

Airbnb your place

Vacation home rentals in Mississippi River

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Mississippi River

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Vacation home in St. Louis

4.87 out of 5 average rating, 201 reviews

Casa Atitlan in Soulard - 2 bed, downtown 5 min

In the heart of Soulard! St. Louis’s most vibrant entertainment district! Drive to baseball & hockey games and walk to dozens of bars and restaurants. 🚘 1.3 mi to Busch Stadium (baseball) 🚘 1.7 mi to Enterprise Center (hockey) 🚘 1.6 mi to The Arch 🚘 1 -2 mi from the 4 major interstates “44, 64, 70, and 55”. 🚘 8.5 mi to Forest Park (Trails, Zoo, & Museum) 🚘 6 mi to BJC & Children’s hospital. This unit features 2 bedrooms, a beautifully decorated living room, and fully stocked kitchen.

Vacation home in Saint Paul

4.94 out of 5 average rating, 196 reviews

King Bed! Historic 2-BR and FREE Parking!

Welcome to our unique luxury home! We are located inside the historical Pioneer Endicott Building, originally built in 1889 and fully remodeled in 2016. We have many options to help you relax whether it's playing on the private pool table, working out in the fully equipped fitness center, or soaking up the sun on the roof top deck with beautiful views of the city! • FREE Parking • In-unit Washer/Dryer • Dishwasher • Free High-speed Internet & WIFI • Secured Entry W/ unique code for every guest

Vacation home in Gresham

4.85 out of 5 average rating, 130 reviews

Modern Lake House w/ Rec Room Garage & Hot Tub!

This extraordinary four bedroom private lake house is the perfect destination for those seeking a way to relax, have fun, enjoy unbelievable forest lakefront views, and experience some of the things our area is known best for. Our detached Rec house gives you a private theater, a pool table, and a corner bar to entertain after a long weekend of hunting and fishing, or cruising our ATV/UTV and snowmobile trails, all within a mile or two. Fully furnished, inside and out. Private dock & Canoe.

Vacation home in Highlandville

4.99 out of 5 average rating, 118 reviews

Two Rivers Guest House (no cleaning fee)

Please read thoroughly: Bike to Two Rivers Mountain Bike Park for a morning ride or relax in a comfortable space after a late evening at Greenhouse Two Rivers. Our place is perfectly situated between the two! This newly constructed private retreat space is conveniently located between between Springfield and Branson. Enjoy relaxing on the spacious deck overlooking the woods, book a blacksmithing or enameling class with us, or use our place as a base while you explore Springfield or Branson.

Vacation home in Hollister

4.96 out of 5 average rating, 119 reviews

Rustic Retreat Lodge. Pool, HOT TUB, game room.

Enjoy your trip to Branson and the Ozarks Mountains while staying at our lodge in Hollister. It is located within minutes of Branson attractions, Table Rock Lake and world class golf courses. Beautifully decorated with rustic touches, stunning handmade furniture made in the USA, plush and soft linens, and a well stocked kitchen. Perfect for family getaways, a romantic retreat, splashing in the lake, catching the shows in town, or just disconnecting and enjoying the beauty of Table Rock Lake.

Vacation home in St. Louis

4.97 out of 5 average rating, 113 reviews

Lovely, updated 2-bedroom apartment in The Grove

Centrally located and spacious 2nd floor apartment with private off-street parking. Updated kitchen with 2nd floor porch with bistro table. Includes Keurig coffee maker and all the basics you will need. Stackable washer/dryer. Bedroom 1 has queen bed with high thread count linens. Bedroom 2 has full bed and lots of natural light. A walk-in closet/office space. Family room is warm & inviting with Roku TV. Beautiful shared patio and fenced in backyard. Enjoy all that St. Louis has to offer!

Vacation home in Tulsa

4.96 out of 5 average rating, 220 reviews

Retro Cherry Street Apartment with Private Balcony

This travel-themed upstairs apartment has its own private balcony and features all you need to be comfortable during your stay, a queen bed, living room with flat screen T.V., bathroom with combination tub/shower, a complete kitchen with dining area, & dedicated workspace. Easily walk to Tulsa's Market District, TU, coffee, yoga, antiques, or groceries. Quick freeway access to enjoy all Tulsa has to offer! This is a pet, smoke, and drug free property. City of Tulsa License: STR22-00177

Vacation home in Bella Vista

4.95 out of 5 average rating, 166 reviews

Getaway to the lake discounts offered in Sept

This isn't just a house, this is an experience! Over 2000sqft dream house with lots of natural lighting. Lake without a steep descent or stairs. Fast Wi-Fi speeds, & tv's (no cable) throughout. All basic (soap, hair dryer) items supplied including a fully equipped kitchen. 6 queen beds, 1 twin bed, 1 sofa twin, & 1 full bed and full futon bed with 2.5 bathrooms (see access section.) Arcade games, in/outside games, a game table for cards/puzzle building, and a full-sized foosball game.

Vacation home in Ontonagon

4.96 out of 5 average rating, 100 reviews

Lake Superior Get-Away

This Lake Superior cottage is perfect for an up north get-away. Enjoy the breathtaking sunsets, strolls along the beach, swimming, kayaking or making your evenings memorable by sitting around the fire pit getting lost in the flames. This Northwoods style home is located 10 minutes from the spectacular Porcupine Mountains. 186' privately owned beach property. At 400 sq ft of living, it comfortably sleeps four with one bedroom and loft area. Two Kayaks are complimentary.

Vacation home in Leona

4.95 out of 5 average rating, 130 reviews

Ranch Lodge-Country Getaway Rockn Rowdy Ranch

If you're looking for a country outdoor getaway destination that provides a perfect escape from the city hustle and bustle, look no further than Rockn Rowdy Ranch located in the small peaceful town of Leona TX - one-half way between Houston & Dallas. Grab your hat & wranglers and come enjoy a reprieve from a hectic life in the city. Enjoy steaks on the grill while watching domestic & exotic animals grazing peacefully in the pasture right in front of your eyes.

Vacation home in Reeds Spring

4.93 out of 5 average rating, 129 reviews

Top Notch Retreat 1 Mile from Silver Dollar City!

Have an unforgettable Branson getaway at our spacious 2-bedroom, 2-bathroom vacation rental that comfortably sleeps 6. Located in a peaceful and private community on a private drive only minutes from Silver Dollar City. You can relax on the patio that overlooks the Ozarks, fish in the private lake, take a hike down one of the nature trails or go swimming in one of the two pools. Whatever you decide to do, we're sure you'll have a great time at our vacation home!

Vacation home in Overland Park

4.92 out of 5 average rating, 108 reviews

Modern Space - Downtown Overland Park

Come and stay at a comfortable yet modern home that includes all of the amenities you could need. This memorable place is anything but ordinary, and we are always looking to beat expectations and go above and beyond for our guests. Centrally located in Downtown Overland Park - Food, coffee, bars, farmer’s markets, and shops are all within walking distance. 15 minutes from the plaza and downtown Kansas City, 25 minutes from Arrowhead stadium and MCI airport.

Vacation rentals for every style

Get the amount of space that is right for you

Bungalows

Intimate homes. inviting architecture

Houses

A space thats all yours, with room for everyone

Apartments

Convenient locations with everyday essentials

Popular amenities for Mississippi River vacation home rentals

Free parking on premises

Air conditioning

Family-friendly vacation home rentals

Vacation home in Bolivar Peninsula

4.91 out of 5 average rating, 115 reviews

SandBarr-Hot tub, arcade, TikiBar, games, 2 kings!

Vacation home in Eureka Springs

4.76 out of 5 average rating, 25 reviews

Peaceful and Serene

Vacation home in Longtown

4.73 out of 5 average rating, 56 reviews

Private beach, quiet cove, beautiful deck view!

Vacation home in Jonesboro

4.92 out of 5 average rating, 75 reviews

Waterfront Escape on Caney Lake

Vacation home in Galveston

4.84 out of 5 average rating, 174 reviews

Sunny Daze...1 block to beach

Vacation home in Cookson

5 out of 5 average rating, 6 reviews

Cozy Turtle cabin @ Lake Tenkiller

Vacation home in New Orleans

4.96 out of 5 average rating, 140 reviews

Serene Uptown Pied-A-Terre

Vacation home rentals with a patio

Vacation home in Greentop

4.88 out of 5 average rating, 51 reviews

Cheerful 2 bedroom home on 3 acres in Greentop, MO

Vacation home in Hot Springs

5 out of 5 average rating, 16 reviews

Sol Bungalow

Vacation home in Rogers

4.98 out of 5 average rating, 85 reviews

Lake View! Hot-Tub! Beaver Lake House!

Vacation home in Osage Beach

5 out of 5 average rating, 16 reviews

Lake House Retreat-No Steps-2b/2ba Margaritaville

Vacation home in Clinton

4.96 out of 5 average rating, 24 reviews

Stunning 4-bedroom Lakehouse on the water!!

Vacation home in Wilburton

4.99 out of 5 average rating, 97 reviews

Peaceful retreat @ Four Star Ranch

Vacation home in Wautoma

4.98 out of 5 average rating, 48 reviews

Blair Lake House

Vacation home in Sunrise Beach

4.96 out of 5 average rating, 25 reviews

Grandparent's Dream-Family Reunion Headquarters

Vacation home rentals with a washer and dryer

Vacation home in Waukon

4.88 out of 5 average rating, 69 reviews

Downtown, 2-bedroom, apartment suite.

Vacation home in Park Rapids

5 out of 5 average rating, 12 reviews

Stony Lake Getaway

Vacation home in Heflin

5 out of 5 average rating, 51 reviews

Secluded Shades of Blue - Lake Bistineau Sunsets

Vacation home in Ames

4.93 out of 5 average rating, 89 reviews

Retreat in a Stunning House

Vacation home in Hot Springs

4.98 out of 5 average rating, 51 reviews

The Country House at Mill Creek Music Farm

Vacation home in Washburn

5 out of 5 average rating, 45 reviews

Historic Hawkes Apartment

Vacation home in Galveston

5 out of 5 average rating, 118 reviews

5 Min Walk To Beach - Hot Tub - Veteran Discounts

Vacation home in Ironton

5 out of 5 average rating, 66 reviews

Cozy Mountain House Retreat close to State Parks.

Destinations to explore