Guesthouse vacation rentals in Orange County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Orange County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Orange County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Cary
4.92 out of 5 average rating, 298 reviewsCentral to Everything, Renovated, Dog Friendly.
Guesthouse in Apex
4.92 out of 5 average rating, 354 reviewsCountry place close to all Triangle locations
Guesthouse in Chapel Hill
4.96 out of 5 average rating, 345 reviewsCozy Secluded Accessible West Wing
Guesthouse in Saxapahaw
4.92 out of 5 average rating, 706 reviewsThe Yurt at Frog Pond Farm
Guesthouse in Durham
4.99 out of 5 average rating, 235 reviewsLaCasita, charming 2-story guest house near Duke
Guesthouse in Durham
4.87 out of 5 average rating, 181 reviewsRockwood Oasis Studio BR Full Bath no kitchen
Guesthouse in Chapel Hill
Serenity Room 12 min. from UNC
Guest house rentals with a patio
Guesthouse in Durham
4.95 out of 5 average rating, 126 reviewsSpotless Scent & Mold-Free Guesthouse Near Duke!
Guesthouse in Mebane
4.93 out of 5 average rating, 30 reviewsMebane Guest House
Guesthouse in Durham
5.0 out of 5 average rating, 12 reviewsNew Apt- walk to everything Rockwood
Guesthouse in Durham
4.98 out of 5 average rating, 88 reviewsGreat Guesthouse Studio Suite w/ hot tub & pool!
Guesthouse in Chapel Hill
5.0 out of 5 average rating, 51 reviewsCarolina Cottage
Guesthouse in Chapel Hill
4.83 out of 5 average rating, 36 reviewsGuesthouse + Access to Morgan Creek Trail
Guesthouse in Holly Springs
5.0 out of 5 average rating, 88 reviews"Wit's End" welcomes you! 2BR comfy guest house
Guesthouse in Durham
5.0 out of 5 average rating, 19 reviews“Meelie Doll”~ Private - Cozy Stdio Apt abv garage
Guest house rentals with a washer and dryer
Guesthouse in Cary
5.0 out of 5 average rating, 117 reviewsGuest House on the Cary Downtown Park!
Guesthouse in Chapel Hill
4.9 out of 5 average rating, 29 reviewsCarolina Hideaway
Guesthouse in Durham
5.0 out of 5 average rating, 57 reviewsDelightfully Durham: Guesthouse with Kitchen!
Guesthouse in Durham
4.91 out of 5 average rating, 92 reviewsAdorable + private guesthouse close to downtown
Guesthouse in Durham
5.0 out of 5 average rating, 16 reviews1 Bedroom Apartment Overlooking Duke Campus East
Guesthouse in Pittsboro
4.96 out of 5 average rating, 25 reviewsThe Sacred Cedar
Guesthouse in Durham
4.94 out of 5 average rating, 48 reviewsDuplex filled with natural light
Guesthouse in Durham
4.91 out of 5 average rating, 65 reviewsDuke Park Carriage house - Studio
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