House vacation rentals in Panama City
Find and book unique houses on Airbnb
Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City house rentals
House rentals with a pool
Home in Panamá
5 out of 5 average rating, 4 reviewsBeautiful house in Brisas del Golf
Home in Provincia de Panamá Oeste
4.79 out of 5 average rating, 28 reviewsLuxurious beach front home in Veracruz
Home in Veracruz
New place to stayCasa Araujo
Home in Panama City
4.93 out of 5 average rating, 28 reviewsCheerful Casa Duplex with swimming pool.
Home in Panamá
4.33 out of 5 average rating, 3 reviewsVilla Helena Los Altos Cerro Azul-3 bedrms & pool
Home in Panamá
4.71 out of 5 average rating, 21 reviewsYour cottage, Mountain Menus, awaits.
Weekly house rentals
Home in Panama City
5 out of 5 average rating, 3 reviewsMountain Retreat
Home in Panamá Oeste
5 out of 5 average rating, 6 reviewsSpecious house that can accommodate up to seven
Home in Panamá
5 out of 5 average rating, 4 reviewsPleasant house equipped for Descanso or homeoffice
Home in Panamá
4.6 out of 5 average rating, 20 reviewsCan Colibrí - Villa in Cerro Azul- Jacuzzi&Sauna
Home in Panamá
New place to stayComfortable and luxurious apartment
Home in Panamá
New place to stayThe Bird's Nest - Cerro Azul
Home in Panamá
3.67 out of 5 average rating, 3 reviewsAn oasis in the middle of town
Quick stats about house rentals in Panama City
Total rentals
450 properties
Nightly prices starting at
$10 before taxes and fees
Total number of reviews
5.4K reviews
Family-friendly rentals
160 properties are a good fit for families
Pet-friendly rentals
130 properties allow pets
Rentals with a pool
90 properties have a pool
Destinations to explore
- Punta Chame Vacation rentals
- Maria Chiquita Vacation rentals
- Playa Blanca Vacation rentals
- Nueva Gorgona Vacation rentals
- Colón Vacation rentals
- Playa Santa Clara Vacation rentals
- Contadora Island Vacation rentals
- La Guaira Vacation rentals
- Anton Valley Vacation rentals
- Chicá Vacation rentals
- San Andrés Vacation rentals
- Cartagena Vacation rentals
- Waterfront rentals Panama City
- Rentals with beach access Panama City
- Hostel rentals Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Pet-friendly rentals Panama City
- Rentals with a sauna Panama City
- Rentals with outdoor seating Panama City
- Rentals with a home theater Panama City
- Monthly Rentals Panama City
- Rentals with pools Panama City
- Beach house rentals Panama City
- Beach condo rentals Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Rentals with an accessible height bed Panama City
- Hotel rentals Panama City
- Fitness-friendly rentals Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Kid-friendly rentals Panama City
- Rentals with lake access Panama City
- Smoking-friendly rentals Panama City
- Rentals with a hot tub Panama City
- Serviced apartment rentals Panama City
- Rentals with a washer and dryer Panama City
- Villa rentals Panama City
- Rentals with a patio Panama City
- Condo rentals Panama City
- Rentals with a fire pit Panama City
- Rentals with an EV charger Panama City
- Rentals with breakfast Panama City
- House rentals Panama
- Tiny house rentals Panama
- Guesthouse rentals Panama
- Townhouse rentals Panama
- Beach house rentals Panama
- Treehouse rentals Panama
- House rentals Panama
- Tiny house rentals Panama
- Guesthouse rentals Panama
- Townhouse rentals Panama
- Beach house rentals Panama
- Treehouse rentals Panama
- House rentals Playa Coronado
- House rentals Altos del Maria
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom