House vacation rentals in Panama
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Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama house rentals
House rentals with a pool
Home in Panama
4.96 out of 5 average rating, 142 reviewsVilla Isabella in Coronado Beach Panama
Home in Bocas Del Toro
4.96 out of 5 average rating, 99 reviewsWiona of Villa Paraiso | Beachfront Villa & Pool
Home in Palenque
4.82 out of 5 average rating, 11 reviewsCaribbean Paradise - Beachfront Getaway
Home in Playa Venao
5 out of 5 average rating, 18 reviewsNearly Oceanfront: Blue 3 Bedroom Spacious Villa
Home in Playa Hermosa
5 out of 5 average rating, 27 reviewsEntire house with private pool facing beach !
Home in Río Hato
4.93 out of 5 average rating, 29 reviewsVilla Santorini | Playa Blanca
Home in Bocas del Toro Province
5 out of 5 average rating, 28 reviewsThe Pool House, Beach House on Paunch Beach
Home in Playa Bluff
4.93 out of 5 average rating, 29 reviewsJungle House 100m from the beach
Weekly house rentals
Home in Altos del Maria
5 out of 5 average rating, 27 reviewsPortazul - A Mountain Retreat
Home in Santa Catalina
4.95 out of 5 average rating, 44 reviewsCasa Colibrí - modern house in the green
Home in Isla Carenero
4.94 out of 5 average rating, 18 reviewsCasa Blanca-Sea Views/outdoor living/walk to surf
Home in Bastimento
4.85 out of 5 average rating, 47 reviewsBay Of The Floating Palms - Beach Front Home
Home in Nueva Gorgona
5 out of 5 average rating, 7 reviewsSpectacular Beachfront House
Home in Torio
5 out of 5 average rating, 14 reviewsIdeal Creative Retreat Immersed in Forest
Home in Jaramillo
4.93 out of 5 average rating, 14 reviewsCastle in the Sky
Home in La Guaira
4.97 out of 5 average rating, 88 reviewsPuntita Manzanillo, fantastic sea and jungle
Private house rentals
Home in Bajo Boquete
4.99 out of 5 average rating, 68 reviewsBeautiful new house in Boquete
Home in Bajo Boquete
4.96 out of 5 average rating, 74 reviewsSpacious 3BR walking distance, close to everything
Home in Boquete
5 out of 5 average rating, 17 reviewsCasa Camila Apartment
Home in Bajo Boquete
4.78 out of 5 average rating, 67 reviews7 sketch mountain Jaramillo house upstairs Boquete
Home in Playa Venao
5 out of 5 average rating, 17 reviewsBeachfront Tropical Chalet Venao with Rancho
Home in San Carlos District
4.93 out of 5 average rating, 72 reviewsBeach Home with Pool and Ocean View.
Home in Santa Fe
4.94 out of 5 average rating, 18 reviewsSanta Fe House with an amazing view
Home in Pedasí
5 out of 5 average rating, 26 reviewsBeautiful Home, Birds, Monkeys, Pool, Trail
Destinations to explore
- Rentals with an accessible height bed Panama
- Bed and breakfasts Panama
- Pet-friendly rentals Panama
- Rentals with a sauna Panama
- Townhouse rentals Panama
- Rentals with a fireplace Panama
- Rentals with a patio Panama
- Loft rentals Panama
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- Boutique hotel rentals Panama
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- Farmstay rentals Panama
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- Monthly Rentals Panama
- Rentals with a hot tub Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Cabin rentals Panama
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- Nature eco lodge rentals Panama
- Rentals with a fire pit Panama
- Beach condo rentals Panama
- Boat rentals Panama
- Rentals with a home theater Panama
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- Tiny house rentals Panama
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- Apartment rentals Panama
- Rentals with an EV charger Panama
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- Island rentals Panama
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- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with pools Panama
- Condo rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- House rentals Panama City
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- House rentals Altos del Maria
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