Boutique hotel vacation rentals in Panama

Find and book unique boutique hotel rentals on Airbnb

Top-rated boutique hotel rentals in Panama

Guests agree: these boutique hotel rentals are highly rated for location, cleanliness, and more.

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Superhost

Hotel room in Bajo Boquete

4.92 out of 5 average rating, 107 reviews

Villa Alejandro - Tastefully Furnished Room

Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Guest favorite

Hotel room in PA

4.88 out of 5 average rating, 25 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Guest favorite

Hotel room in Bastimentos Island

4.95 out of 5 average rating, 63 reviews

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

Hotel room in San Carlos

4.79 out of 5 average rating, 109 reviews

B) Beach, surf and Relax with King size bed

Manglar Lodge is a small beach Hotel located at El Palmar beach on the Pacific coast on the town of San Carlos, If you like nature and comfort, you'll enjoy your stay at Manglar Lodge We are small beach hotel that offers the visitor four cozy and clean rooms, WiFi, restaurant (open form 8.30am until 9pm) with great food and a great selection of craft beer and live music on some weekends from 7pm to 9.30pm The Room is on a 1 floor you have to walk up the stairs

Guest favorite

Hotel room in Playa Venao

5 out of 5 average rating, 9 reviews

Brisa - Ocean Views, Calm Vibes, King/Twin beds

Brisa is the perfect family room on the ground floor, made for relaxing after a fun day in the sun. Equipped with a mini fridge, AC, TV (ready for you to sign into all your online viewing accounts), hot/cold water and beautiful breezy covered seating area outside with ocean views. Steps from our pool! *Additional guest, available to kids up to 12 year old* *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host. *

Guest favorite

Hotel room in Cambutal

5 out of 5 average rating, 8 reviews

Boutique Inn_The Hill 4_Private Entry_16+

The Hill Panama, our Boutique Inn Adult Only (16+) is located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 4 was designed as a boutique hotel room with separated private entry, greenery view and communal kitchen.

Superhost

Hotel room in Bajo Boquete

4.77 out of 5 average rating, 83 reviews

Buena Vista Boquete Quadruple Room

This quadruple room is furnished with one double bed and two twin beds, all with semi-orthopedic mattresses. The room has a WiFi access, a Smart TV, large windows to enjoy the mountain view and a private bathroom. Features: Large windows / Bathroom / Access to rooftop patio with 360° views / Access to kitchen / WiFi / Smart TV / Standing fan / Parking

Guest favorite

Hotel room in Panamá

4.87 out of 5 average rating, 39 reviews

Private rooms Sofia's B&B Hostal Boutique

Boutique hostel accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. The fee shown by Airbnb for your reservation distributes 2 guests per room, that is, guests must share beds and/or rooms. If you require a special room distribution for your group, please contact the host first, as the rate may vary.

Guest favorite

Hotel room in Isla Colon

4.92 out of 5 average rating, 37 reviews

Studio space with one queen bed and sitting area

Studio space – 1 queen bed 1 queen size bed | sitting area | patio with garden view | lower level of hotel room details: Room with one queen size bed Sitting area Patio with garden view Bathroom with rain water shower Office desk Closet Air conditioning Coffee pot with grinder and gourmet panamanian coffee beans Flat screen tv Lower level room

Superhost

Hotel room in El Valle de Antón

4.58 out of 5 average rating, 12 reviews

Suite medievale natura & arte

La Corte del Re é un hotel boutique composto da un insieme di suite con tematica medievale immerse nel bosco dove arte e natura si fondono nel cuore del Valle di Anton. A pochi passi dal centro sono dotate di tutti i confort e contano con un parco privato, piscina e parcheggio. Sono suite e pertanto non dispongono di una cucina.

Guest favorite

Hotel room in Las Tablas Abajo

4.82 out of 5 average rating, 67 reviews

Blue Room for 2 - Luxury right on the beach!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.