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Mansion vacation rentals in Panama

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Top-rated mansion rentals in Panama

Guests agree: these mansions are highly rated for location, cleanliness, and more.

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Home in Bastimentos

4.81 out of 5 average rating, 107 reviews

Spacious, Over the Water Home with Plunge Pool

Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Condo in Buenaventura, El Chirú

4.99 out of 5 average rating, 113 reviews

Stylish & Quiet ~ Breathtaking Laguna Views ~Pool

➡️ The highest rated w more than 60 reviews! ⬅️ Welcome to "The Gliding Damselfly," the MOST stylish 4BR 4Bath flat nestled in the majestic Buenaventura, perfect for escaping city crowds and enjoying mesmerizing views, stunning beaches (5 mins), and lavish pools (2 mins). Explore the area and its exciting attractions, and then retreat to the breathtaking sanctuary that will leave you in awe. ✔ 4 Comfy BRs ✔ Open Design Living ✔ Full Kitchen ✔ Terrace ✔ Smart TVs ✔ Fast Wi-Fi See more below!

Earthen home in El Cope, Penonome

4.92 out of 5 average rating, 153 reviews

Beautiful Eco House in Panama

We are very pleased to offer our beautiful, modern, comfortable house designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and escape daily stress. It is in a beautiful part of Panama near a cloud forest national park. The house sits in 17 acres of forest and has 2 rivers for swimming. The house is very open allowing full enjoyment of nature. There are amazing hiking opportunities in the mountains with waterfalls and visits to local communities.

Home in San Carlos

4.94 out of 5 average rating, 100 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 7.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base price covers 4 guests (additional charge $40 per person). Sleeps up to 25 guests.

Villa in Punta Chame

4.99 out of 5 average rating, 110 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 236 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets. any inquiry please contact 66168596

Condo in Panamá

4.95 out of 5 average rating, 177 reviews

Los Diamantes Maximo. Prepare to be stunned.

A penthouse apartment, "Maximo" is in an ancestral home of a famous Panamanian family. 2 levels, 4 bedrooms, 3 of which have en-suite bathrooms, 5 meter ceilings, a huge rooftop terrace overlooking the ocean, and also with an enormous balcony overlooking Plaza Herrera, the heart of Casco Viejo. Need more space in the same building? We also have these properties. Add the path to airbnb.com to view: /h/terraza2 /h/herrera3 /h/cuteroomdiamantes

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 199 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Home in Río Hato

4.98 out of 5 average rating, 112 reviews

Renewed / Make yourself at Home / Enjoy

Cozy & comfy villa with great illumination and natural ventilation located in the Playa Blanca Beach & Lagoon complex in Rio Hato, Cocle just 10 minutes away from Scarlett Martinez International Airport and 90 minutes from Panama City. Playa Blanca is an exclusive tourist residential beach complex with villas, apartments, big lush green areas, the largest pool in Central America, beach club, Playa Blanca Hotel Resort and much more.

Home in El Valle de Antón

4.94 out of 5 average rating, 133 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Cottage in Altos del Maria

4.93 out of 5 average rating, 116 reviews

Mountain Cottage with Great View and Heated Pool

Casa de Montaña, with spectacular views of the mountains of Altos del María, perfect to rest or spend it with family, with heated pool, spacious outdoor spaces, Smart TV and A/A in all rooms, WIFI throughout the property and fully equipped. Includes Prime Video service. It has fire pit and a gas fired BBQ. For weekend rentals saliendo Domingo, se da da late check out complimentary.

Villa in Farallon

4.9 out of 5 average rating, 209 reviews

4 Bedroom Costa Blanca Golf & Beach Villa

Spacious 4 bedroom, 4.5 bathroom, 250m detached villa overlooking the 7th putting green on Mantaraya Golf Course. Accommodation provided for up to 12 people within 4 bedrooms. The 15m long swimming pool plus shallow area in rear garden is totally private. Villa guests have access to the Property Owners Beach Club and Restaurant.

Vacation rentals for every style

Get the amount of space that is right for you

Cottages

Quaint homes, peaceful surroundings

Cabins

Kick off your hiking boots at these rustic lodgings

Bungalows

Intimate homes. inviting architecture

Popular amenities for Panama mansion rentals

Free parking on premises

Air conditioning

Luxury mansion rentals

Rental unit in Maria Chiquita

5 out of 5 average rating, 18 reviews

Playa Escondida ocean and lagoon #vacfamilia

Villa in Playa Venao

4.8 out of 5 average rating, 44 reviews

Villa Nomada -Barefoot Luxury Beach Front Villa

Villa in San José

4.82 out of 5 average rating, 38 reviews

10% OFF | Luxury Mini Resort House @Punta Barco

Villa in Panamá

4.98 out of 5 average rating, 65 reviews

Beautiful House in Panama w/ King Beds + Pool

Villa in Boquete

5 out of 5 average rating, 5 reviews

The perfect weather in Finca San José, Boquete

Villa in Vista Mar Golf, Beach & Marina

4.92 out of 5 average rating, 25 reviews

The Golf Oasis Villa by AcoModo

Home in Bajo Boquete

4.78 out of 5 average rating, 67 reviews

7 sketch mountain Jaramillo house upstairs Boquete

Rental unit in Maria Chiquita

4.96 out of 5 average rating, 23 reviews

Penthouse in Playa Escondida 4 bedrooms

Pet-friendly mansion rentals

Vacation home in San Carlos

4.89 out of 5 average rating, 37 reviews

Welcome to our house in Playa Corona

Home in Provincia de Panamá Oeste

4.79 out of 5 average rating, 28 reviews

Luxurious beach front home in Veracruz

Home in Palenque

4.82 out of 5 average rating, 11 reviews

Caribbean Paradise - Beachfront Getaway

Home in Coronado

4.71 out of 5 average rating, 21 reviews

CHARMING ALMAR FRONT HOUSE WITH PISCINA-CORONADO

Rental unit in San Carlos District

4.98 out of 5 average rating, 99 reviews

Amazing Oceanfront apartment in San Carlos

Rental unit in Buenaventura

5 out of 5 average rating, 82 reviews

Exclusive apartment steps from the sea in Puntarena

Home in Nueva Gorgona

5 out of 5 average rating, 7 reviews

Spectacular Beachfront House

Home in Playa Bluff

4.93 out of 5 average rating, 29 reviews

Jungle House 100m from the beach

Mansion rentals with a pool

Villa in Río Hato

5 out of 5 average rating, 25 reviews

Villa Agueda Decameron, Golf Club & Pool

Condo in El Chirú

4.87 out of 5 average rating, 93 reviews

Buenaventura beach condo with private pool

Home in Gamboa

4.87 out of 5 average rating, 93 reviews

BirdHouse@ Gamboa Panama Canal

Home in PA

4.8 out of 5 average rating, 90 reviews

Villa GiGi - Beach Home Panama Santa Clara

Rental unit in Panama City

4.96 out of 5 average rating, 24 reviews

22M Spectacular Penthouse New Design Oceanview

Rental unit in Maria Chiquita

4.86 out of 5 average rating, 21 reviews

Playa Escondida, luxury ocean view apartment

Condo in San Carlos District

4.95 out of 5 average rating, 39 reviews

Punta Caelo Beach Front View

Townhouse in Nueva Gorgona

5 out of 5 average rating, 3 reviews

Lux Beachfront Oasis in Gorgona

Destinations to explore