House vacation rentals in Panhandle

Find and book unique houses on Airbnb

Top-rated house rentals in Panhandle

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Guest favorite

Home in Amarillo

4.96 out of 5 average rating, 350 reviews

Cozy 2 bedroom German Cottage.

Enjoy this cozy, unique, and tranquil getaway. It’s 575 sqft/ 1 1/2 blocks from Route 66. Sits back from the street at the end of a long, double wide, steep, driveway. There’s trees on the property. One bedroom has a queen size bed and the other a twin. Enjoy the sunset on the back deck. A 50 inch smart tv is in the living room. Make your coffee or tea and enjoy the can of cinnamon rolls in the refrigerator ready to bake. Stroll down Route 66, with its many antique shops, restaurants, and bars.

Guest favorite

Home in Amarillo

5 out of 5 average rating, 276 reviews

The Bunny Bungalow

Enjoy a relaxing getaway for two in our brand new bungalow. The studio design features everything you need in one convenient living space - a king bed with fresh white cotton bedding and luxe pillows, comfy chairs for enjoying the fireplace and TV, intimate dining area and a stylish kitchen. The bath features a double vanity, tub for two and modern shower. A full size laundry set is tucked near the back door. The back yard features a cedar pergola with hot tub, a seating area and gas BBQ grill.

Guest favorite

Home in Amarillo

4.84 out of 5 average rating, 540 reviews

The Gallery

You'll have a great time at this comfortable place. It is a quaint space. It was built in the 1930s as a home/convenient store. Prior to Airbnb it was an art gallery. All the art is for sale and changes frequently. It is a 4 block walk to downtown with 30 restaurants, a 7 block walk to Hodge Town Ball Park and the Civic Center. Conveniently located to I-27 and I-40. There is a large fenced area behind the Airbnb for dog lovers! It is self-check-in any time you get here. No cleaning/pet fees.

Guest favorite

Home in Amarillo

4.99 out of 5 average rating, 364 reviews

Relaxing Bungalow Efficiency with private parking.

Kick back and relax in this calm, stylish space with private driveway parking. All newly remodeled, modern features with some original 1950s character. Small kitchenette with sink, refrigerator, microwave, small convection oven and newest smart keurig coffee machine. Large outdoor deck with plenty of seating area, private off street driveway parking for 2 cars, side street parking for large vehicle/trucks. Beautiful quiet neighborhood centrally located and very easy access to I-40 or I-27.

Guest favorite

Home in Amarillo

4.9 out of 5 average rating, 671 reviews

Country Club Cutie (Washer/Dryer.) No pets!

Cozy 3 bedroom house with beautiful but creaky, hardwood floors with easy access to Rails to Trails path that is perfect for walking, riding bikes, or watching beautiful West Texas sunsets. Large backyard. Washer and dryer in property. Quiet street . Full size fridge and central heat and air. Ask me about our supportive running community. Easy access to I40 to see the Cadillac ranch and beautiful Palo Duro Canyon. Please consider my request for no pets and no smoking in my home.

Guest favorite

Home in Amarillo

4.98 out of 5 average rating, 530 reviews

Olsen Oasis with Tesla Charger

Stay in comfort and class in this fully updated, stylish home. Conveniently charge your Tesla in the 2-car garage or cook your favorite meal in an open kitchen with top of the line appliances and quartz countertops. If cooking isn't your thing, you are centrally located so you can get anywhere in Amarillo in about 10 minutes! There are games to choose from, or three TVs to entertain you while you stay. Located less than 1 mile from I-40 and less than 3 miles from BSA Hospital.

Guest favorite

Home in Amarillo

4.99 out of 5 average rating, 410 reviews

💎1919 Downtown Jewel 💎 W/ basement and office

Whether you are passing through or staying a while, you will love our stylish updated historical downtown craftsman. Located just off of I-27 and I-40, you have easy access to everything. You are walking distance from Hodgetown, the Amarillo Civic Center, Amarillo Globe News Performing Arts Center, and many great local restaurants and bars! If you are in the mood to just hang out and chill we have several outdoor spaces for you to enjoy as well! Our jewel has it all!

Guest favorite

Home in Amarillo

4.99 out of 5 average rating, 181 reviews

Barstow Restful Retreat ❤️ Clean&Quiet&Stocked

Welcome to the retreat on Barstow! We aren’t new at hosting and you won’t be disappointed! Ultra Clean, Comfy Beds and Quiet Neighborhood. Suitable for travelers near and far, short or long term and perfect for kids and families. Located in City View on a street that feeds directly into South Loop 335 for easy access. Just minutes away from shopping, eating, Palo Duro Canyon State Park, TEXAS Outdoor Musical, West Texas A&M University, I-27 and more.

Guest favorite

Home in Amarillo

4.96 out of 5 average rating, 691 reviews

Hubbell Duplex "Side A" on Historic Route 66

CENTRAL HEATING & AIR, WASHER & DRYER, WIFI & CABLE Get your kicks on Route 66. Located on Route 66, the Hubbell Duplex A is part of the Sixth Street Historic District. There are plenty of restaurants and antique stores in historic buildings. Master bedroom with king bed, 2nd bedroom is very small and only has a day bed. There is a queen blow up mattress that will sleep 2. Pet accommodations are $25 for each pet. Thank you.

Guest favorite

Home in Amarillo

4.96 out of 5 average rating, 137 reviews

Charming Amarillo Hideaway

This charming home, recently updated, offers a perfect blend of modern amenities and cozy comfort, all while being centrally located for ultimate convenience. As you step inside, you're greeted by a warm and inviting atmosphere. The kitchen boasts new appliances and sleek countertops, providing both functionality and style. This house is not just a place to stay; it's a home that offers a warm embrace to all who enter.

Guest favorite

Home in Amarillo

4.99 out of 5 average rating, 213 reviews

Bent Oak Haven located on a Culdesac - sleeps 9

Bent Oak Haven is a beautiful home in a residential neighborhood on a cul-de-sac, just minutes from the hospital district and I40. This home can sleep up to 9 guests, has an open living area with a gas fireplace, a private patio with a gas grill and table and chairs to enjoy the nice evenings. A television is in each sleeping area with Disney, Hulu and ESPN+. There is a ring doorbell and contactless entry.

Superhost

Home in Amarillo

4.86 out of 5 average rating, 466 reviews

Sunrise Cottage *with a HOT TUB*

Close enough to the city for convenience, but far enough out to be able to enjoy the view of the stars at night! Rest well in our charming Bohemian cottage with 1 King and 1 Queen bed with pillow toppers, fast wifi, coffee & comfortable front porch swing to enjoy the Sunrise & Sunset!