Hotel vacation rentals in South Carolina
Find and book unique hotel rentals on Airbnb
Top-rated hotel rentals in South Carolina
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for South Carolina hotel rentals
Family-friendly hotel rentals
Hotel room in Myrtle Beach
4.09 out of 5 average rating, 122 reviewsSerendipity Queen Room w/ en Suite
Hotel room in Edisto Island
5 out of 5 average rating, 12 reviewsWyndham Ocean Ridge - Edisto Island ** 1 Bedroom
Superhost
Hotel room in Clemson
5 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Private room in Myrtle Beach
4.6 out of 5 average rating, 97 reviewsCarolinian 731 -direct oceanfront suite! Sleeps 6!
Private room in Myrtle Beach
5 out of 5 average rating, 3 reviewsBeach Access Resort 2bdrm condo
Private room in Charleston
4.73 out of 5 average rating, 407 reviewsThe Goldman Room @ The Annex
Hotel rentals with a pool
Superhost
Private room in North Myrtle Beach
5 out of 5 average rating, 5 reviews(A670) One Bedroom Ocean Front Condo, SC
Guest favorite
Private room in Irmo
5 out of 5 average rating, 15 reviewsRelax in beach themed room.
Superhost
Hotel room in Charleston
4.86 out of 5 average rating, 7 reviewsFlavor-forward dining and craft cocktails
Superhost
Private room in Pawleys Island
4.77 out of 5 average rating, 44 reviewsBubbles Up at Litchfield By The Sea
Guest favorite
Hotel room in Myrtle Beach
4.92 out of 5 average rating, 12 reviewsNew to Airbnb! Oceanfront 2 bedroom Condo
Guest favorite
Private room in Myrtle Beach
4.86 out of 5 average rating, 7 reviewsOceanfront paradise, waterpark, pools, 4 hot tubs
Guest favorite
Resort in Surfside Beach
4.94 out of 5 average rating, 18 reviewsSurfside Beach Getaway: 2BR Suite at Grand Palms
Superhost
Hotel room in Myrtle Beach
4.78 out of 5 average rating, 18 reviewsNewly Renovated 1BR DirOceanfront Gem Heated pools
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