Vacation rentals in Upstate South Carolina

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Top-rated vacation rentals in Upstate South Carolina

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

Cottage in Lyman

4.99 out of 5 average rating, 235 reviews

Lakeside Retreat

With quiet views on Lyman Lake in South Carolina, this cottage is a great place to rest and relax. Close to Greenville and Spartanburg, SC. You’ll love my place because of the location, the ambiance, and the outdoor space. My place is good for couples, solo adventurers, and business travelers. GSP Airport-7 miles, Peace Center/Downtown Greenville-15 miles, Downtown Spartanburg-15 miles, Clemson Univ-42 miles, Furman Univ-14 miles, Tryon- 14 miles, Charlotte Airport-73 miles Asheville-46 mi

Guest favorite

Guesthouse in Abbeville

4.97 out of 5 average rating, 287 reviews

Quiet, Peaceful Loft in the Woods

Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

Guest favorite

Shipping container in Walhalla

4.98 out of 5 average rating, 409 reviews

The Southern Cross at Hi Saw Gap

The quintessential Tiny Home experience at beautiful Hi Saw Gap! The Southern Cross is located cliff's edge with endless views over untouched natural beauty. Fabulous outdoor amenities compel you to be outside, including a glass enclosed shelter, propane fire pit, charcoal BBQ grill, and covered bistro deck with outdoor kitchen and prep station. Located just a half-mile from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and the World class Stumphouse Mountain Bike Park.

Guest favorite

Guesthouse in Greenville

4.99 out of 5 average rating, 359 reviews

The Cottage at Old Oaks Farm

Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Guest favorite

Cottage in Donalds

4.98 out of 5 average rating, 311 reviews

Affordable Luxury / Quiet / 2 min to Erskine

Quiet, peaceful & secluded, Serenity Lane Cottage is the perfect place to call home away from home! Built new in Fall of 2019! It is located next door to Erskine college. We have added a side patio with a charcoal grill and dining table! Your own private lane and parking, full kitchen, coffee maker & coffee, laundry facilities, and dishwasher make staying with us relaxing and enjoyable! Our location says Donald’s but we are actually on the outside of Due West and Erskine College.

Guest favorite

Cabin in Cleveland

4.97 out of 5 average rating, 388 reviews

Wahoo Cabin

The cabin sits on 5 acres of land and has so much privacy. We are 15 miles from "Pretty Place Chapel" and there are 3 state parks within 10 miles that include hundreds of waterfalls and trails. The cabin is surrounded by so many outdoor activities to take advantage of! If you like camping, this is camping with a flare. Wahoo Cabin is cozy and comfy so that you feel at home and as a part of nature. We look forward to sharing this beautiful and unique area and Wahoo Cabin with you.

Guest favorite

Home in Greenville

4.99 out of 5 average rating, 131 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Guest favorite

Shipping container in Easley

4.99 out of 5 average rating, 191 reviews

Romantic lakefront container home

Start your next adventure at The Hive at Addison Farms! Upon arrival, you will be greeted with an incredible, picturesque view of Saluda Lake. This carefully designed romantic retreat is the ultimate getaway to unwind, reconnect, and relax. The Hive is conveniently located less than 20 mins. from Downtown Greenville, making it the perfect destination for a secluded weekend away, yet close enough to explore the wonderful places and activities in Upstate, SC.

Guest favorite

Dome in Travelers Rest

4.99 out of 5 average rating, 108 reviews

Treetop Getaway w/ Hot Tub • Peaceful retreat

Welcome to Treetop Getaway! Escape to your own enchanting oasis, nestled high among the trees in this stunning dome retreat! Situated on a private 14 acres with a stream running through the middle of the property, this luxurious and cozy hideaway offers the perfect setting for relaxation, reconnection, and rest. Book now and treat yourself to an unforgettable experience filled with comfort, natural beauty, and cherished moments. We can't wait to host you!

Guest favorite

Farm stay in Easley

4.99 out of 5 average rating, 189 reviews

Dogwood Cottage- farm charm - Greenville & Clemson

A retreat in and of itself! This perfect, peaceful cottage is complete with full kitchen, bath and private porch. This converted llama barn elevates reclaimed woods and metals into a darling spot on our 24 acre farm. Serene and tranquil yet only minutes from downtown Greenville or Clemson activities. Nature galore with walking, fishing and even farm animals to meet. Our farm sits at the foot of the Blue Ridge with many quaint mountain towns to visit.

Guest favorite

Treehouse in Mountain Rest

5.0 out of 5 average rating, 350 reviews

THE BELLA LUNA Romantic Mountain Treehouse

Come Sleep in the Trees - Luxury Romantic Treehouse above Walhalla, in upstate SC is just minutes from Stumphouse Tunnel, Stumphouse Mountain Bike Park, Issaqueena Falls & white water rafting. Oconee County has many beautiful waterfalls & hiking trails. We are close to Clemson, Lake Keowee, Lake Hartwell & Lake Jocassee and located just inside Sumter National Forest. An AMAZING ROMANTIC GETAWAY for HONEYMOONS, ANNIVERSARIES & BIRTHDAYS!

Guest favorite

Cabin in Donalds

4.98 out of 5 average rating, 393 reviews

Cabin in the woods

aprx. 4 miles to Erskine college, Good for couples, solo adventurers, business travelers, and furry friends (pets).11 miles from Abbeville~Birth of the confederacy. aprox. 60 miles to Augusta Ga the masters golf tour. aprx. 40 miles to Clemson U. Available walking trails down to stream and around the farm. Fishing dock . Plenty of parking. The Diamond Hill Mine in Abbeville is about 17 miles from here.