Are there vacation rentals with a dedicated workspace in Cape Girardeau?

Yes! Work meets play with ease at over 90 vacation rentals in Cape Girardeau featuring dedicated workspaces. Stay connected and productive in your home away from home.

Are there pet-friendly vacation rentals in Cape Girardeau?

Four-legged friends are welcome in Cape Girardeau. Choose from more than 50 vacation rentals for guests traveling with pets.

How much does it cost to stay in apartment rentals in Cape Girardeau?

Experience the best of Cape Girardeau with our apartment rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

Do house rentals in Cape Girardeau have wifi?

Absolutely! We offer over 70 house rentals with wifi in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.

Are there family-friendly apartment rentals in Cape Girardeau?

Cape Girardeau has more than 20 family-friendly apartment rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

Do house rentals in Cape Girardeau have a bbq area?

Absolutely! We offer over 10 house rentals with a bbq area in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.

Do house rentals in Cape Girardeau have air conditioning?

Absolutely! We offer over 70 house rentals with air conditioning in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.

What are the most popular amenities for Apartment Rentals in Cape Girardeau?

Enhance your stay in our Apartment Rentals with the most popular amenities: over 40 homes with wifi, over 40 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

Cape Girardeau vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Cape Girardeau

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Cabin in Black River Township

4.98 out of 5 average rating, 62 reviews

Well-Designed Cozy Cabin near lake and hiking

Designed for families as a relaxing spot to get away from the hustle & bustle of life, the "Hillside Hideaway" is a 2 bedroom, 1 bath cabin perched on a hill in southeastern Missouri with a gorgeous sunset view from the screen porch. We have a well-stocked kitchen, laundry, fire pit, and plenty of toys and games for the whole family. It is just a couple of miles to a sandy swimming beach at Lake Wappapello, the boat ramp at Chaonia Landing, and many hiking trails in Lake Wappapello State Park.

Superhost

Cabin in Fredericktown

4.91 out of 5 average rating, 280 reviews

Hot tub/ Blissful Beaver River Cabin

Remodeled remote cabin with an antique modern feel, large deck overlooking the St.Francis River. Soak your cares away in the Hot Tub. The river is great for kayaking and fishing. Enjoy a peaceful nature get away. Bring your fishing poles, a book, kayaks and disconnect from the hustle and bustle of everyday life! We’re close to Silver Mines,Millstream Gardens, Taum Sauk Mountain, Amidon Conservation, Elephant Rocks, only 10 miles to Ironton or Fredericktown for food, drinks, golf and wineries!

Guest favorite

Cabin in Alto Pass

4.99 out of 5 average rating, 249 reviews

Ma's Cabin, Alto Pass, IL. Fine country lodging.

Cute and country remodel done in 2019. Recent new appliances, furnishings, flooring, heat & A/C, washer & dryer. Cabin is secluded and quiet plus 1/2 mile from Alto Pass Lookout Point and right in the middle of many award-winning wineries. 15 miles from Carbondale 4 miles from Giant City 30 miles from Garden of the Gods 6 lakes within 10-mile radius Hundreds of miles of hiking trails in nearby Shawnee National Forest 6 miles from Bald Knob Cross Please, no dogs! No smoking in cabin!

Guest favorite

Treehouse in Greenville

5 out of 5 average rating, 207 reviews

Secluded couple's treehouse "The Roost" w/hot tub

"The Roost" is rustic but not primitive treehouse 2 hrs south of St Louis near Wappapello Lake. Yes it has indoor plumbing & running water. Accommodates two adults, has a fully equipped kitchen and breakfast items are provided for you to cook. Surrounded by thousands of acres of national forest. Observe wildlife sightings from the deck while soaking in the hot tub, sleep comfortably in a queen size pillowtop Serta bed on a Motion Air base, and relax as you enjoy the ambience of the fireplace.

Guest favorite

Home in Cobden

4.92 out of 5 average rating, 49 reviews

Skyline Getaways

Forget your worries in this spacious and serene space. Whether you are enjoying the wine trails, a girl’s trip, hiking the trails, a family vacation or even a fishing trip, our place is the place for you! Take in all the area has to offer and then relax and rest easy in the comfort of our home. End your day relaxing by the pool, soaking in the hot tub, or enjoy a nice campfire. Very close to Bald Knob Cross. Come stay and wash your worries away! Cameras actively recording at all times.

Superhost

Condo in Creal Springs

4.67 out of 5 average rating, 15 reviews

Fish~Boat~Beach~Relax @ The Blue Heron

Important to note: This home is separated into two units. The entire upper floor is used for guests to enjoy and the lower level is occupied by the owner's son. There is a door that links the two floors but locks from both sides. Take a break and unwind at this peaceful oasis. Beautiful lakefront property that offers incredible amenities including a private beach, boat dock with electricity, firepit, hammock, waterfall/koi pond, large spacious deck with outdoor dining and propane grill.

Superhost

Home in Carbondale

4.76 out of 5 average rating, 133 reviews

Brick Estate with pool in Quiet Neighborhood

Large fully furnished 4 BR, 3 BTH house in a beautiful, quiet neighborhood in Carbondale. Private pool & large backyard. Very safe & walkable neighborhood. Inspected and licensed by the City of Carbondale. Carbondale Vacation Rental Unit License Number 24-06. Basement with bar, pool table, ping pong. Complete kitchen with all utensils & cookware. Garden patio w/ Weber grill, tables, chairs, beautiful landscaping, etc. ***Pool is open from Memorial Day through Labor Day***

Superhost

Cottage in Ste. Genevieve

4.73 out of 5 average rating, 163 reviews

Ruby’s Rental

If you are looking for a unique, eclectic, fun place to get away, welcome to ruby's rental!!! Walk just 3.5 blocks to downtown historic Ste Genevieve. Come for the weekend, relax, stroll, drink wine, and eat lunch with Ruby's big sister Stella at Stella and Me Cafe At main and Washington Ruby’s Rental has one bedroom (sleeps-2), a sleeping loft (sleeps-2), and a Murphy Bed (sleeps-2) in the living room. Hot Tub, Fire Pit- Please provide your own wood

Guest favorite

Home in Lost Creek Township

4.91 out of 5 average rating, 78 reviews

Camp Bluegill Lake House

New, modern, and cozy with tons of amenities and activities. Relax in the hot tub overlooking the private lake or lounge on the private beach and watch the kids have fun in the paddle boat. Beautiful, secluded property on 5 acres. Tons of parking and easy in and out access for trailers and covered parking. Minutes from beaches, boat ramps and marinas on beautiful Lake Wappapello. Multiple state parks, trails and recreational activities also within minutes.

Guest favorite

Guest suite in Ste. Genevieve

4.94 out of 5 average rating, 120 reviews

La Fleur de Lis STG

We invite you to stay, relax, and enjoy your time in our community! Enter through your own private patio into a warm & relaxing living room with a leather sofa & loveseat. High speed internet, a modern work station, & cable TV. The bedroom nook has a comfortable king size bed. Full bath. The kitchenette has a full size refrigerator, sink, microwave, toaster, and Keurig, The dining area is roomy with a table & chairs. No cleanin, or add on fees.

Superhost

Home in Goreville

4.8 out of 5 average rating, 10 reviews

New! Modern! Lake House Escape! Hot Tub!

Amazing! Lake House Escape views are abundant from this waterfront lake house! With totally unobstructed views of the water from Living area, your family can kick back and relax as the boats go by. The elegant-yet-casual vacation rental has 5 bedrooms, 3 bathrooms spacious living areas overlooking the Bay, and a modern kitchen. Take out the kayaks and Paddle Boards and explore the shore or lounge on the private peninsula and enjoy peaceful location.

Guest favorite

Cottage in Marion

4.98 out of 5 average rating, 255 reviews

Lakefront cottage Lake of Egypt -Kayaks, breakfast

SUPER HOSTS 7 years straight/high customer rating! Back open after remodel! *Lake front lounging area; stone steps into the lake! Lakefront cottage w/ 2 open docks, HUGE screened porch overlooking lake. Fish & swim off our 2 docks! Sleeps Max 6. Full kitchen, washer/dryer. 2 kayaks. Grill, charcoal, fire pit & firewood. We supply bread, bacon, milk & farm eggs! Only non shedding 25lb or less Pets; must be pre-approved. 3 Night minimum stay.

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Cape Girardeau vacation rentals

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Air conditioning

Stay near Cape Girardeau's top sights

Minglewood Brewery13 locals recommend

Port Cape13 locals recommend

Katy O'Ferrell's Publick House9 locals recommend

Top of the Marq8 locals recommend

Isle of Capri Casino8 locals recommend

Coin-Op Cantina7 locals recommend

Other great vacation rentals in Cape Girardeau

Guest favorite

Cabin in Perryville

5 out of 5 average rating, 43 reviews

Escape At Eagle View

Guest favorite

Cabin in Bonne Terre

4.95 out of 5 average rating, 630 reviews

The Waterfront cottage

Guest favorite

Home in Jackson

4.93 out of 5 average rating, 156 reviews

*County Club 439*

Guest favorite

Home in Carterville

4.94 out of 5 average rating, 36 reviews

Alta Home

Guest favorite

Cabin in Goreville

4.92 out of 5 average rating, 64 reviews

Double Down Cabin in the Woods (Upper Level)

Guest favorite

Home in Carbondale

5 out of 5 average rating, 11 reviews

Owls Nest

Superhost

Home in Creal Springs

4.69 out of 5 average rating, 35 reviews

Gone Fish’n is a 4 bed/2bath home w/large boatdock

Guest favorite

Home in Marion

5 out of 5 average rating, 21 reviews

lakehome 2. 3 bed room. pontoon available to rent

Show all

Quick stats about vacation rentals in Cape Girardeau

Total rentals
160 properties
Nightly prices starting at
$20 before taxes and fees
Total number of reviews
9K reviews
Family-friendly rentals
80 properties are a good fit for families
Pet-friendly rentals
50 properties allow pets
Rentals with dedicated workspaces
90 properties have a dedicated workspace

Frequently Asked Questions

Are there vacation rentals with a dedicated workspace in Cape Girardeau?
Yes! Work meets play with ease at over 90 vacation rentals in Cape Girardeau featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there pet-friendly vacation rentals in Cape Girardeau?
Four-legged friends are welcome in Cape Girardeau. Choose from more than 50 vacation rentals for guests traveling with pets.
How much does it cost to stay in apartment rentals in Cape Girardeau?
Experience the best of Cape Girardeau with our apartment rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Cape Girardeau have wifi?
Absolutely! We offer over 70 house rentals with wifi in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.
Are there family-friendly apartment rentals in Cape Girardeau?
Cape Girardeau has more than 20 family-friendly apartment rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do house rentals in Cape Girardeau have a bbq area?
Absolutely! We offer over 10 house rentals with a bbq area in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Cape Girardeau have air conditioning?
Absolutely! We offer over 70 house rentals with air conditioning in Cape Girardeau. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for Apartment Rentals in Cape Girardeau?
Enhance your stay in our Apartment Rentals with the most popular amenities: over 40 homes with wifi, over 40 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

Cape Girardeau vacation rentals

Top-rated vacation rentals in Cape Girardeau

Vacation rentals for every style

Cabins

Houses

Apartments

Popular amenities for Cape Girardeau vacation rentals

Stay near Cape Girardeau's top sights

Other great vacation rentals in Cape Girardeau

Cabin in Perryville

Cabin in Bonne Terre

Home in Jackson

Home in Carterville

Cabin in Goreville

Home in Carbondale

Home in Creal Springs

Home in Marion

Quick stats about vacation rentals in Cape Girardeau

Total rentals

Nightly prices starting at

Total number of reviews

Family-friendly rentals

Pet-friendly rentals

Rentals with dedicated workspaces

Frequently Asked Questions

Are there vacation rentals with a dedicated workspace in Cape Girardeau?

Are there pet-friendly vacation rentals in Cape Girardeau?

How much does it cost to stay in apartment rentals in Cape Girardeau?

Do house rentals in Cape Girardeau have wifi?

Are there family-friendly apartment rentals in Cape Girardeau?

Do house rentals in Cape Girardeau have a bbq area?

Do house rentals in Cape Girardeau have air conditioning?

What are the most popular amenities for Apartment Rentals in Cape Girardeau?

Destinations to explore