House vacation rentals in Cape Girardeau
Find and book unique houses on Airbnb
Top-rated house rentals in Cape Girardeau
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Cape Girardeau house rentals
House rentals with a pool
Home in Ste. Genevieve
5 out of 5 average rating, 67 reviewsSecluded Private Cabin with Pool, hot tub, firepla
Home in Marion
4.82 out of 5 average rating, 28 reviewsLakehouse-indoor pool and hottub
Home in Cobden
4.92 out of 5 average rating, 49 reviewsSkyline Getaways
Home in Carbondale
New place to stayPond/Pool/Fire pit/Pet Friendly
Home in Park Hills
4.98 out of 5 average rating, 63 reviewsBluebird Meadows w/ Hot Tub and Pool **Special***
Home in Du Quoin
4.89 out of 5 average rating, 150 reviewsMarsha's Guesthouse Rental
Home in Cape Girardeau
4.7 out of 5 average rating, 210 reviews3+ acre: Swimming Pool/Mini Golf/Pool Table/Nature
Home in Cobden
5 out of 5 average rating, 10 reviewsDomaine de Champagne
Weekly house rentals
Home in Anna
4.91 out of 5 average rating, 22 reviews150 year old charmer!
Home in Cobden
5 out of 5 average rating, 35 reviewsSouth Pass Hideaway
Home in Alto Pass
4.98 out of 5 average rating, 42 reviewsAlto Cabin-Enjoy the Area’s Fall Events!
Home in Sikeston
5 out of 5 average rating, 11 reviewsEmma’s Cottage
Home in Advance
4.81 out of 5 average rating, 21 reviewsWillow Acres - 2/2 home with BBQ and outdoor patio
Home in Sikeston
4.91 out of 5 average rating, 92 reviewsNeuberry Cottage
Home in Bardwell
5 out of 5 average rating, 31 reviewsCharming Country Home
Home in Perryville
5 out of 5 average rating, 15 reviewsGerman-Inspired Home in Perryville
Private house rentals
Home in Dexter
4.9 out of 5 average rating, 91 reviewsHome Away from Home
Home in Marion
4.99 out of 5 average rating, 70 reviewsFarmhouse Cottage
Home in Benton
4.95 out of 5 average rating, 57 reviewsBackroad Breeze
Home in Kevil
5 out of 5 average rating, 59 reviewsHosta House
Home in Farmington
5 out of 5 average rating, 66 reviewsColumbia Street Carriage House
Home in Fredericktown
4.91 out of 5 average rating, 45 reviewsThe GooseNest
Home in Farmington
5 out of 5 average rating, 32 reviewsThe Weber House
Home in Ste. Genevieve
5 out of 5 average rating, 19 reviewsThe Breeze-cozy vintage charm
Quick stats about house rentals in Cape Girardeau
Total rentals
70 properties
Nightly prices starting at
$20 before taxes and fees
Total number of reviews
3.3K reviews
Family-friendly rentals
40 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with dedicated workspaces
50 properties have a dedicated workspace
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