Guesthouse vacation rentals in Charleston County
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Top-rated guesthouse rentals in Charleston County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
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Popular amenities for Charleston County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 350 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in Charleston
4.92 out of 5 average rating, 308 reviewsMother in Law in James Island Riverland Terrace
Guesthouse in Summerville
4.94 out of 5 average rating, 215 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Charleston
4.91 out of 5 average rating, 654 reviewsIsland Oasis—Near Downtown
Guesthouse in Ridgeville
4.82 out of 5 average rating, 215 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 228 reviewsGreen Garden Studio @greengardenstudio2017
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 100 reviews5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Guesthouse in Johns Island
4.98 out of 5 average rating, 240 reviewsPrivate waterfront apt in the oaks
Guest house rentals with a patio
Guesthouse in Charleston
4.96 out of 5 average rating, 132 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Charleston
4.98 out of 5 average rating, 127 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Johns Island
4.91 out of 5 average rating, 113 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Hanahan
4.99 out of 5 average rating, 83 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Charleston
4.94 out of 5 average rating, 82 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in Goose Creek
4.96 out of 5 average rating, 51 reviewsThe Blue Secret
Guesthouse in Charleston
4.95 out of 5 average rating, 93 reviewsBoHo styled casita in adorable neighborhood...
Guesthouse in Charleston
5.0 out of 5 average rating, 26 reviews1/1 sleeps 3 ADU Modern+Amazing!
Guest house rentals with a washer and dryer
Guesthouse in Charleston
4.9 out of 5 average rating, 554 reviewsCute, Cozy, Charleston Cottage
Guesthouse in Charleston
4.99 out of 5 average rating, 209 reviewsRedesigned suite! 12min to city, pet-friendly
Guesthouse in Charleston
4.99 out of 5 average rating, 150 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in Charleston
4.98 out of 5 average rating, 246 reviewsDetached Guest Suite
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 260 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Charleston
5.0 out of 5 average rating, 222 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 442 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 119 reviewsBeach, downtown, Alhambra Hall weddings so close!
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