Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Ridgeville
4.82 out of 5 average rating, 215 reviewsPond House Bungalow at Natural Gathering Grounds
Guesthouse in Charleston
4.91 out of 5 average rating, 650 reviewsIsland OasisβNear Downtown
Guesthouse in Johns Island
4.98 out of 5 average rating, 240 reviewsPrivate waterfront apt in the oaks
Guesthouse in Summerville
4.94 out of 5 average rating, 213 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in North Charleston
4.86 out of 5 average rating, 443 reviewsPark Circle Jungalow Loft
Guesthouse in Mount Pleasant
4.95 out of 5 average rating, 224 reviewsGreen Garden Studio @greengardenstudio2017
Guesthouse in Summerville
4.87 out of 5 average rating, 749 reviewsNew Loft in Historic Summerville
Guesthouse in Charleston
4.93 out of 5 average rating, 318 reviewsCozy Island Cottage
Guest house rentals with a patio
Guesthouse in Charleston
4.97 out of 5 average rating, 130 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Charleston
4.98 out of 5 average rating, 125 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Johns Island
4.91 out of 5 average rating, 109 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Hanahan
4.99 out of 5 average rating, 80 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Charleston
4.94 out of 5 average rating, 80 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in Charleston
5.0 out of 5 average rating, 14 reviewsLowcountry Guesthouse
Guesthouse in Goose Creek
4.96 out of 5 average rating, 50 reviewsThe Blue Secret
Guesthouse in Charleston
5.0 out of 5 average rating, 15 reviewsGas Light Carriage House James Island
Guest house rentals with a washer and dryer
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 253 reviewsShem Creek Bungalow: Coastal Comfort Redefined
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 222 reviewsCozy Apartment in Mount Pleasant
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 258 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Charleston
4.98 out of 5 average rating, 245 reviewsDetached Guest Suite
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 439 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Guesthouse in Charleston
4.99 out of 5 average rating, 146 reviewsLarge Guesthouse with Private Dock & Marsh Views
Guesthouse in Charleston
5.0 out of 5 average rating, 220 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 118 reviewsBeach, downtown, Alhambra Hall weddings so close!
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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