Guesthouse vacation rentals in Charleston Harbor

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Top-rated guesthouse rentals in Charleston Harbor

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Guest favorite

Guesthouse in Mount Pleasant

4.97 out of 5 average rating, 239 reviews

Cozy Apartment in Mount Pleasant

Our place is a cozy and bright garage apartment. It has one bedroom, living room with sleeper sofa, a full bath with tub and fully equipped kitchen. We hope this provides that home away from home feel in a relaxed, yet inviting setting. It is close to dining, the beach and a ten minute ride across the bridge to Charleston. You’ll love our place because of the coziness and the location. Our place is good for couples, solo adventurers, and business travelers. STRPermit# ST240232 SCBUSLIC#20122393

Guest favorite

Guesthouse in Mount Pleasant

4.98 out of 5 average rating, 274 reviews

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!

#1 VOTED by AirBnB '21/'23! Newly built in 2018 fully furnished apartment. 700 sq ft one br w/Queen bed & walk-in closet. Spacious Living rm w/full size Futon. One bath w/shower & tub. Washer & dryer, full kitchen w/ stainless steel appliances. Modern amenities, WIFI, Netflix, all soaps, hair dryer, iron, luggage stands & a whole lot more. Private drive up parking! Our place in the Old Village is within stone's throw to Folly Beach, Downtown Charleston, and Sullivan's Island/Isle of Palms.

Guest favorite

Guesthouse in Mount Pleasant

4.98 out of 5 average rating, 220 reviews

Charleston Guesthouse

Conveniently nestled in the heart of Mt. Pleasant and only a short car ride from the best that Charleston has to offer. Minutes away from historic sites such as Boone Hall Plantation, Palmetto Island County Park, Belle Hall shopping center and many other attractions. Centrally located between Isle of Palms/Sullivan's beaches and downtown Charleston. Located in a peaceful, family friendly community reminiscent of old country living. Sit back and enjoy the quietness of your home away from home.

Guest favorite

Guesthouse in Charleston

4.93 out of 5 average rating, 737 reviews

Charleston's Coolest Neighborhood

You can't beat the location! You'll be 5-10 minutes from downtown Charleston, but with free off-street parking, AND you can walk to dozens of bars, restaurants, coffee shops, etc. Avondale is Central to all parts of Charleston, and its a cinch to drive to everywhere from here. This studio apartment is private, modern, and newly renovated. You'll have a kitchenette, grill, outdoor seating, and access to beach equipment. Also only a 5 minute walk to the West Ashley Greenway for biking/jogging!

Guest favorite

Guesthouse in Charleston

4.94 out of 5 average rating, 212 reviews

Quaint Cottage Studio in Ashley Forest (Avondale)

Take in the peace, calm, and hospitality of Charleston at this small, quaint, stand-alone cottage. The studio is situated on our property and shares an outdoor lounge and dining area. Located in the neighborhood of Ashley Forest, a small corner of Avondale, you are walking distance to breweries, cafes, wine bars, sushi restaurants and more. Downtown is a 10 minute ride share away, and there is also a bus stop five minutes from the property that will take you to the heart of King Street.

Guest favorite

Guesthouse in Mount Pleasant

4.99 out of 5 average rating, 131 reviews

Groves Carriage House, near Shem Creek

Charming, quiet, secure guest house located a short walk from Shem Creek, restaurants, grocery (Trader Joe's), neighborhood park. Close to the bridge, 10 minutes to downtown, and 10 minutes from Sullivan's Island. Private entrance and reserved parking space. 1 King bed , 1 bath, full kitchen, and Queen sleeper sofa. Pack/play and high chair available. WIFI and washer/dryer. There will be a small addition for a Local Occupancy Tax. STR PERMIT #: ST240112 Mt.P BUS. LIC. #: 20120642

Guest favorite

Guesthouse in Charleston

4.78 out of 5 average rating, 505 reviews

Private Guest House - Pets Welcome! #2023-04560

Perfect for vacation or medical rotations! Detached apartment with private entrance located in Charleston's highly-sought-after Riverland Terrace neighborhood. The unit is located less than 10 minutes from downtown Charleston and the medical district, 15 minutes from Folly Beach, and abuts the Charleston Municipal Golf Course. The unit features a private bath, kitchenette, full-size refrigerator, pull-out sofa, and backyard with a six-foot privacy fence and swing set. Pets are welcome.

Guest favorite

Guesthouse in Mount Pleasant

4.97 out of 5 average rating, 480 reviews

Old Mt. Pleasant/Shem Creek close to Sullivans/DT

This 1 bed/1 bathroom bungalow sits among the Old Mt. Pleasant neighborhood off Coleman Blvd, which is only 3 mi. to Sullivans Island Beach, <1 mi. to Shem Creek! A quick ride will land you in bustling downtown Charleston. Close to the stunning Pitt St Bridge to watch the sunset. Walk popular Coleman Blvd which boasts restaurants, shops, boutiques and fitness venues alike, only 1 block away. 3 grocery stores <1 mi. Quiet, clean, and quaint! STR Permit #ST250014 MP Bus Lic #20115373

Guest favorite

Guesthouse in Mount Pleasant

4.96 out of 5 average rating, 101 reviews

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

LOCATION, LOCATION, LOCATION! Welcome to Persimmon Place, a brand new guesthouse in the heart of Old Village in Mt. Pleasant. Historic Old Village is one of Charleston's most beautiful neighborhoods, central to all Charleston has to offer. This 2BR 1 BA is the perfect spot for your Lowcountry visit. -Walk to Shem Creek with bars, restaurants, & water activities -Less than 4 miles(8 min drive)to Sullivan's Island Beach -5 miles(9 min drive)to downtown Charleston ST240164 BL20127902

Guest favorite

Guesthouse in Mount Pleasant

4.97 out of 5 average rating, 215 reviews

Charming Charleston Carriage House

Enjoy a stylish, renovated carriage house in Charleston. An ideal escape for couples (sleeps two comfortably), it features a kitchenette (refrigerator, dishwasher, and coffee maker), separate living and bedroom areas, a full bath, and outdoor space. It is centrally located in a quiet Mt. Pleasant neighborhood, 6 miles to the beaches of Isle of Palms and Sullivan's Island and 5 miles to downtown Charleston. Town of Mount Pleasant STR Permit ST240220 MP Business License #20126985

Guest favorite

Guesthouse in Charleston

4.98 out of 5 average rating, 224 reviews

Cottage Under the Oaks

A lovely cottage centrally located on James Island, The Cottage is about 5 miles to Folly Beach or Downtown. There are a few restaurants within walking distance, and almost everything on the island is within 5 miles. *No children under 13 without prior approval.* **We do have a 30-day minimum during some dates. If you need a shorter reservation and your dates aren’t showing as available, message us and we’ll see if we can make it work.** Permit Number: OP2021-01970

Guest favorite

Guesthouse in Charleston

4.97 out of 5 average rating, 360 reviews

Daniel Island Getaway

Welcome to your home away from home near Center Park on Daniel Island, located within 20 minutes from Downtown Charleston, Sullivan’s Island and Isle of Palms. This almost 600sqft above garage guest house has a separate bedroom and full bathroom in addition to a spacious living room with a Queen sofa bed and a kitchen area that will meet all of your basic needs. The kitchen includes a Keurig, microwave and griddle. There is even an outdoor shower for guests to use.